Gemcitabine hydrochloride | CAS No. 122111-03-9

Gemcitabine hydrochloride

Basic Information

CAS Number

122111-03-9

Molecular Formula

C9H12ClF2N3O4

Molecular Weight

299.66 g/mol

AD

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

292°C

Boiling Point

No data available

Density

==

Flash Point

245.7℃

Solubility

H2O: ≥10mg/mL

Refractive Index

268

Vapor Pressure

No data available

Specific Rotation

+43 °- +50° (c=1, water)

C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl

InChI

InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1

InChIKey

OKKDEIYWILRZIA-OSZBKLCCSA-N

LogP

-0.8668

Topological Polar Surface Area

110.60000000000001 Ų

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

426

Safety Information

View Safety Information

GHS Hazard Pictograms

H360H360

Hazard Statement

H360 May damage fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

  • 2'-Deoxy-2',2'-difluorocytidine monohydrochloride
  • Gemcitabine hydrochloride, United States Pharmacopeia (USP) Reference Standard
  • 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride
  • EN300-7361886
  • MFCD01735988
  • Gemcitabine (as hydrochloride)
  • 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride
  • INFUGEM
  • GEMCITABINE HYDROCHLORIDE [USP MONOGRAPH]
  • LY-188011
  • dFdC
  • NCGC00168784-01
  • AKOS015999730
  • MLS003915643
  • CS-0755
  • BDBM50247964
  • 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride
  • s1149
  • 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one hydrochloride
  • 2'-deoxy-2',2'-difluorocytidine, hydrochloride
  • 2',2'-Difluoro-2'-deoxycytidine hydrochloride
  • 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-onehydrochloride
  • 2'-DEOXY-2',2'-DIFLUOROCYTIDINE MONOHYDROCHLORIDE (.BETA.-ISOMER)
  • Gemcitabine (Hydrochloride)
  • CHEBI:31647
  • 2',2'-Difluorodeoxycytidine monohydrochloride
  • 2'-Deoxy-2',2'-difluorocytidine HCL
  • GEMCITABINE HYDROCHLORIDE [EP MONOGRAPH]
  • LY 188011
  • BG164501
  • Gemcitabine Hydrochloride,Gemzar, LY-188011

MDL Number

MFCD01735988

Customs Code

2934999090

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