5-Cyanopyrazine-2-carboxylic acid

Basic Information

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CAS Number

1211533-09-3

Molecular Formula

C6H3N3O2

Molecular Weight

149.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

328.6±15.0°C at 760 mmHg

SMILES

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C1=C(N=CC(=N1)C(=O)O)C#N

InChI

InChI=1S/C6H3N3O2/c7-1-4-2-9-5(3-8-4)6(10)11/h2-3H,(H,10,11)

InChIKey

NYZNLFBHQJKDGO-UHFFFAOYSA-N

Complexity

207

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Cyanopyrazine-2-carboxylic acid
NYZNLFBHQJKDGO-UHFFFAOYSA-N
5-cyano-pyrazine-2-carboxylic acid
2-Pyrazinecarboxylic acid, 5-cyano-
AK137311
Z2255112615
5-cyanopyrazine-2-carboxylic acid
MFCD22070527
AKOS022172083
5-Cyanopyrazine-2-carboxylicacid
SCHEMBL11023993
O11418
DB-107587
1211533-09-3
DS-5823
Z1416192764
SY120715
DTXSID40742139
EN300-149224
CS-0097641
A891906

MDL Number

MFCD22070527

FAQ

What are the physical and chemical properties of 5-Cyanopyrazine-2-carboxylic acid (CAS: 1211533-09-3)?

5-Cyanopyrazine-2-carboxylic acid is a white crystalline solid with a molecular weight of 198.14 g/mol. It has a melting point of 236-238°C and is slightly soluble in water. This compound is reactive towards nucleophiles and can undergo amide formation and cyanation reactions.

How is 5-Cyanopyrazine-2-carboxylic acid (CAS: 1211533-09-3) typically synthesized?

5-Cyanopyrazine-2-carboxylic acid can be synthesized via direct cyanation of 5-pyrazinecarboxylic acid using sodium cyanide in the presence of a base like sodium hydroxide. The yield is typically around 85-90%, with good selectivity for the target product.

What industries use 5-Cyanopyrazine-2-carboxylic acid (CAS: 1211533-09-3)?

5-Cyanopyrazine-2-carboxylic acid finds applications in the pharmaceutical industry, particularly in the synthesis of drugs targeting inflammation and pain. It is also used in the polymer industry for the development of new materials with improved properties.

What precautions should be taken when handling 5-Cyanopyrazine-2-carboxylic acid (CAS: 1211533-09-3)?

When handling 5-Cyanopyrazine-2-carboxylic acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated fume hood to avoid inhalation. Ensure proper storage in a cool, dry place away from heat sources and incompatible materials. Always refer to the Safety Data Sheet (SDS) for specific safety guidelines.