Ac-rC Phosphoramidite

Basic Information

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CAS Number

121058-88-6

Molecular Formula

C47H64N5O9PSi

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

InChI

InChI=1S/H3N/h1H3

InChIKey

QGZKDVFQNNGYKY-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

1560

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

Ac-rCPhosphoramidite
121058-88-6
PD158383
DTXSID00743122
CS-W023256
AKOS015999121
Ac-rC Phosphoramidite
N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
N-Acetyl-5/'-O-(4,4-dimethoxytrityl)-2/'-O-[(tert-butyl)dimethylsilyl]cytidine-3/'-(2-cyanoethyl-N,N
HY-W042357
4-Acetamido-1-(5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-O-[tert-butyl(dimethyl)silyl]-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-beta-L-ribofuranosyl)pyrimidin-2(1H)-one
N-{1-[(2S,3S,4S,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-[(tert-butyldimethylsilyl)oxy]oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}acetamide
(2S,3S,4S,5S)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-O-DMT-2'-TBDMS-rC(N-Ac)-3'-CEDPA
2'-TBDMS -Ac-rC-CE-Phosphoramidite
Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
DMT-2′O-TBDMS-rC(ac) Phosphoramidite
N4-ACETYL-2'-O-TERT-BUTYLDIMETHYLSILYL-5'-O-DMT-CYTIDINE 3'-CE PHOSPHORAMIDITE
N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-cytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
2’-TBDMS-rC(N-Ac) Phosphoramidite
5'-DMT-2'-TBDMS-rC(N-Ac) Phosphoramidite
REF DUPL: 2'-TBDMS-rC(N-ac) Phosphoramidite
5'-DMT-2'-O-TBDMS- N4-Acetyl-Cytidine Phosphoramidite
5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite
5'-DMT-2'-O-TBDMS-N4-acetyl-cytidine phosphoramidite
N-[1-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-
DMT-2'O-TBDMS-rC(ac) Phosphoramidite
DMT-2'O-TBDMS-rC(ac) Phosphoramidite, configured for ABI
DMT-2'O-TBDMS-rC(ac) Phosphoramidite, configured for MerMade
Dmt-2'o-tbdms-rc(ac) amidite

MDL Number

MFCD09842111

Customs Code

29349990

FAQ

What regulatory guidelines apply to Ac-rC Phosphoramidite (CAS: 121058-88-6)?

Ac-rC Phosphoramidite (CAS: 121058-88-6) falls under the scope of the REACH regulation in the EU and the TSCA in the USA. It is also classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a flammable liquid. FDA and EPA regulations may also apply due to its use in pharmaceutical and chemical industries. Strict handling and storage guidelines are required to ensure safety and compliance with local and international regulations.

Are there alternatives to Ac-rC Phosphoramidite (CAS: 121058-88-6) in synthesis?

There are several alternatives to Ac-rC Phosphoramidite (CAS: 121058-88-6) in synthesis, including other phosphoramidites and nucleoside derivatives. Common alternatives include N6-Phosphoramidites and 2'-deoxyribonucleoside phosphoramidites. These alternatives offer similar functionalities but with varying chemical properties and reactivity profiles, making them suitable for different synthetic pathways.

What is the market or research trend for Ac-rC Phosphoramidite (CAS: 121058-88-6)?

Ac-rC Phosphoramidite (CAS: 121058-88-6) is a key component in oligonucleotide synthesis, particularly in the field of genetic engineering and drug development. Market trends indicate a steady demand driven by advancements in personalized medicine and gene therapy. Research is focusing on improving synthesis efficiency and developing new applications in biotechnology and diagnostics.

How should waste containing Ac-rC Phosphoramidite (CAS: 121058-88-6) be handled?

Waste containing Ac-rC Phosphoramidite (CAS: 121058-88-6) should be collected in dedicated containers and stored in a secure, well-ventilated area. Incineration is a recommended disposal method, following local regulations. Alternatively, professional waste disposal services can handle the waste, ensuring proper disposal and minimizing environmental impact. Always ensure that all safety precautions are followed to protect both personnel and the environment.