5-Nitro-1,3-thiazol-2-amine | CAS No. 121-66-4

Q: What is 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4)?

5-Nitro-1,3-thiazol-2-amine is a heterocyclic compound with the chemical formula C3H3N3O2S. It contains a thiazole ring substituted with a nitro group and an amino group. This compound is known for its aromatic properties and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.

Q: What are the main uses of 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4)?

5-Nitro-1,3-thiazol-2-amine is primarily used in the pharmaceutical industry as a building block for the synthesis of drugs targeting neurological and respiratory conditions. It also finds applications in agrochemicals, dyes, and research for developing new chemical compounds with specific functionalities.

Q: Is 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4) safe?

5-Nitro-1,3-thiazol-2-amine is considered toxic if inhaled or ingested. It should be handled with appropriate protective measures such as gloves, goggles, and a fume hood. Safety standards recommend following OSHA and EPA guidelines to ensure proper disposal and minimize exposure risks.

Q: How should 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4) be stored?

5-Nitro-1,3-thiazol-2-amine should be stored in a cool, dry, and well-ventilated area away from light. It is best kept in a sealed container made of glass or polyethylene to prevent moisture absorption. Storage should maintain a temperature below 25°C and avoid exposure to air and heat to ensure stability.

5-Nitro-1,3-thiazol-2-amine

Basic Information

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CAS Number

121-66-4

Molecular Formula

C3H3N3O2S

Molecular Weight

145.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Powder

Melting Point

195-200 °C (dec.)

Boiling Point

345.1°Cat760mmHg

Water Solubility

<0.1 g/100 mL at 20 ºC

Flash Point

162.5°C

Solubility

95% ethanol: soluble1g/150g at 20°C

Refractive Index

1.6740 (estimate)

SMILES

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C1=C(SC(=N1)N)[N+](=O)[O-]

InChI

InChI=1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5)

InChIKey

MIHADVKEHAFNPG-UHFFFAOYSA-N

LogP

log Kow = 0.83

Complexity

125

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.

Sensitiveness

Light Sensitive

Synonyms & References

English

UNII-1GR77A37Z5
SB31744
AC-2989
2-AMINO-5-NITROTHIAZOLE [MI]
4-27-00-04675 (Beilstein Handbook Reference)
121-66-4
AI3-50030
Tox21_303575
Enheptin
PS-3292
STR02181
A0381
DTXCID8066
CCRIS 37
DTXSID6020066
U7458
BP-10109
Aminonitrothiazole
2-Amino-5-nitrothiazole, 97%
F0001-0347
NCGC00091644-02
CAS-121-66-4
SCHEMBL375929
Enheptin-T
2-AMINO-5-NITROTHIAZOLE
A804773
5-Nitro-1,3-thiazol-2-amine #
NS00002376
entramine
Aminzol soluble
Tox21_202377

MDL Number

MFCD00005326

Customs Code

2934100090

FAQ

What is 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4)?

5-Nitro-1,3-thiazol-2-amine is a heterocyclic compound with the chemical formula C3H3N3O2S. It contains a thiazole ring substituted with a nitro group and an amino group. This compound is known for its aromatic properties and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.

What are the main uses of 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4)?

5-Nitro-1,3-thiazol-2-amine is primarily used in the pharmaceutical industry as a building block for the synthesis of drugs targeting neurological and respiratory conditions. It also finds applications in agrochemicals, dyes, and research for developing new chemical compounds with specific functionalities.

Is 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4) safe?

5-Nitro-1,3-thiazol-2-amine is considered toxic if inhaled or ingested. It should be handled with appropriate protective measures such as gloves, goggles, and a fume hood. Safety standards recommend following OSHA and EPA guidelines to ensure proper disposal and minimize exposure risks.

How should 5-Nitro-1,3-thiazol-2-amine (CAS: 121-66-4) be stored?

5-Nitro-1,3-thiazol-2-amine should be stored in a cool, dry, and well-ventilated area away from light. It is best kept in a sealed container made of glass or polyethylene to prevent moisture absorption. Storage should maintain a temperature below 25°C and avoid exposure to air and heat to ensure stability.