N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide | CAS No. 1208319-26-9

N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide

Basic Information

CAS Number

1208319-26-9

Molecular Formula

C15H23N5O2S

Molecular Weight

337.45 g/mol

AD

Basic Physical Properties

CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(c2ncnc3c2cc[nH]3)C

InChI

InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-

InChIKey

HJWLJNBZVZDLAQ-HAQNSBGRSA-N

LogP

1.5020999999999995

Topological Polar Surface Area

90.97999999999999 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

487

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

  • N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide
  • Oclacitinib
  • JAKi
  • trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-cyclohexanemethanesulfonamide
  • 99GS5XTB51
  • PF03394197
  • N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
  • Apoquel
  • N-Methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
  • Oclacitinib [USAN:INN]
  • N-methyl-1-(4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
  • N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesu

MDL Number

MFCD25976611

FAQ

What regulatory guidelines apply to N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9)?

N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) falls under the regulatory framework of the Chemicals of Very High Concern (SVHC) as identified by REACH. It is also subject to the GHS classification, requiring proper labeling and safety data sheets. FDA and EPA have specific guidelines for the handling and disposal of this compound to ensure environmental and worker safety.

Are there alternatives to N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) in synthesis?

There are several alternatives to N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) in synthesis, including 2-methyl-4-(4-(1-methylcyclohexyl)pyrimidin-5-ylamino)pyrimidine and 1-(4-(1-methylcyclohexyl)pyrimidin-5-ylamino)ethanesulfonamide. These alternatives may offer similar functionality with varying chemical properties and synthesis pathways.

What is the market or research trend for N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9)?

N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) is currently trending in research for its potential in medicinal chemistry and pharmaceutical applications. Market trends indicate increasing interest in this compound for its anti-inflammatory and antiviral properties, with ongoing studies exploring its therapeutic potential.

How should waste containing N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) be handled?

Waste containing N-Methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}methanesulfonamide (CAS: 1208319-26-9) should be collected in appropriate containers and labeled with the correct hazard warnings. For disposal, it is recommended to consult with a professional waste management service to ensure the compound is handled according to local and international regulations, including incineration or safe landfilling methods to minimize environmental impact.

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