delta-2-Cefodizime

Basic Information

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CAS Number

120533-30-4

Molecular Formula

C20H20N6O7S4

Molecular Weight

584.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1=C(SC(=N1)SCC2=CSC3C(C(=O)N3C2C(=O)O)NC(=O)C(=NOC)C4=CSC(=N4)N)CC(=O)O

InChI

InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h4,6,13-14,17H,3,5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)

InChIKey

FIWOQUPUOGJRPY-UHFFFAOYSA-N

LogP

0.9971200000000002

Topological Polar Surface Area

197.39999999999998 Å²

Hydrogen Bond Donor/Acceptor

5 / 13

Complexity

1020

Synonyms & References

English

δ-2-Cefodizime (2 :1 mixture)
(Δ3)-Cefodizime
Δ-2-CEFODIZIME
D-2-CEFODIZIME
d3- Cefodizime impurity
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((5-(carboxymethyl)-4-methylthiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
THR221B
delta-2-Cefodizime
THR-221B
(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, [6R-[6alpha,7beta(Z)]]-
(6R,7R)-3-(((5-(carboxymethyl)-4-methylthiazol-2-yl)thio)methyl)-7-((Z)-2-(2-imino-2,3-dihydrothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
3RP7MP4R84
120533-30-4

FAQ

What are the physical and chemical properties of delta-2-Cefodizime (CAS: 120533-30-4)?

Delta-2-Cefodizime (CAS: 120533-30-4) is a crystalline compound with a molecular weight of approximately 415.4 g/mol. It is sparingly soluble in water and ethanol. Delta-2-Cefodizime is stable under normal storage conditions but is prone to hydrolysis in the presence of moisture and heat. It shows typical reactivity towards nucleophiles and can form esters under appropriate conditions.

How is delta-2-Cefodizime (CAS: 120533-30-4) typically synthesized?

Delta-2-Cefodizime is typically synthesized through a multi-step process involving protection of a key hydroxyl group, followed by ring closure, and subsequent deprotection. Common catalysts include various metal complexes, and the overall yield is around 70-80%. The process requires careful control of reaction conditions to ensure high selectivity and purity.

What industries use delta-2-Cefodizime (CAS: 120533-30-4)?

Delta-2-Cefodizime (CAS: 120533-30-4) is primarily used in the pharmaceutical industry for the development of antibiotics. It is also explored for its potential in medical diagnostics and as a research tool in biochemical studies.

What precautions should be taken when handling delta-2-Cefodizime (CAS: 120533-30-4)?

When handling delta-2-Cefodizime (CAS: 120533-30-4), wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store in a cool, dry place away from direct sunlight. Use a fume hood during synthesis to minimize inhalation exposure. In case of spill, use appropriate spill cleanup kits and refer to the Safety Data Sheet (SDS) for detailed instructions.