Anastrozole EP Impurity H (Anastrozole USP Related Compound A) | CAS No. 120511-72-0
Anastrozole EP Impurity H (Anastrozole USP Related Compound A)
Basic Information
CAS Number
120511-72-0
Molecular Formula
C15H18N2
Molecular Weight
226.32 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
129-133°C
Boiling Point
339.1°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- MFCD08062446
- a,a,a',a'-Tetramethyl-5-methyl-1,3-benzenediacetonitrile
- alpha , alpha , alpha , alpha -Tetramethyl-5-methyl-1,3-benzenediacetonitrile
- 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile)
- 2,2'-(5-METHYL-1,3-PHENYLENE)DI(2-METHYLPROPANENITRILE)
- FT-0642939
- DTXSID40581005
- A804525
- Anastrozole impurity H [EP]
- Anastrozole Impurity A
- alpha,alpha,alpha',alpha',5-Pentamethyl-1,3 benzenediacetonitrile
- ?,?,?',?'-Tetramethyl-5-methyl-1,3-benzenediacetonitrile
- 2,2,2'2'-(5-Methyl-1,3-phenylene)-dimethyl-propionitrile
- 3,5-Bis(2-cyanoprop-2-yl)toluene
- 3,5-bis(1-cyano-1-methylethyl)toluene
- 3E89N64V9Z
- Anastrozole Impurity I
- 3,5-Di[(2,2-Dimethyl)Cyanomethyl]Toluene
- CS-B0753
- AS-13156
- ANASTROZOLE IMPURITY H [EP IMPURITY]
- SJECEXNMZXMXNE-UHFFFAOYSA-N
- AKOS005257888
- 1,3-BENZENEDIACETONITRILE, .ALPHA.1,.ALPHA.1,.ALPHA.3,.ALPHA.3,5-PENTAMETHYL-
- 2,2'-(5-methyl-1,3-phenylene)-di-(2-methylpropionitrile)
- 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile
- 2,2 inverted exclamation mark -(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile)
- 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropiononitrile)
- 2 pound not2'-(5-Methyl-1 pound not3-phenylene)bis(2-methylpropanenitrile)
- SCHEMBL1172829
- 2,2'-(5-Methylbenzene-1,3-diyl)bis(2-methylpropanenitrile)
MDL Number
MFCD08062446
Customs Code
2926909090
FAQ
What is Anastrozole EP Impurity H (Anastrozole USP Related Compound A) (CAS: 120511-72-0)?
Anastrozole EP Impurity H, also known as Anastrozole USP Related Compound A, is a chemical compound with CAS number 120511-72-0. It is a known impurity in the synthesis of Anastrozole, a non-steroidal selective aromatase inhibitor used in cancer treatment. This compound typically appears as a white to off-white solid and has a molecular formula of C15H16O3. It is characterized by its structural similarity to Anastrozole and its potential role in pharmaceutical quality control.
What are the main uses of Anastrozole EP Impurity H (Anastrozole USP Related Compound A) (CAS: 120511-72-0)?
Anastrozole EP Impurity H is primarily used in pharmaceutical quality control to identify and quantify impurities during the production of Anastrozole. It is also relevant in research for studying the purity and stability of aromatase inhibitors. In some cases, it may be used as a reference standard for method validation in analytical chemistry. Its use is limited to controlled environments due to its potential as a contaminant in drug manufacturing.
Is Anastrozole EP Impurity H (Anastrozole USP Related Compound A) (CAS: 120511-72-0) safe?
Anastrozole EP Impurity H is generally considered safe when handled properly in controlled environments. However, as an impurity, it may pose health risks if exposure occurs, especially through inhalation or ingestion. Safety measures include using appropriate personal protective equipment (PPE) and following standard chemical handling protocols. Its safety profile is largely determined by the conditions of use and the level of exposure.
How should Anastrozole EP Impurity H (Anastrozole USP Related Compound A) (CAS: 120511-72-0) be stored?
Anastrozole EP Impurity H should be stored in a cool, dry, and dark place, ideally at 2-8°C. It should be kept in a sealed container to prevent moisture and contamination. Avoid exposure to direct sunlight and maintain low humidity levels to ensure stability. Proper storage is crucial for preserving the compound's integrity and ensuring its suitability for analytical purposes.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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