Biapenem | CAS No. 120410-24-4

Biapenem

Basic Information

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CAS Number

120410-24-4

Molecular Formula

C15H18N4O4S

Molecular Weight

350.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

235-242°C

Solubility

H2O: ≥5mg/mL (warmed)

Specific Rotation

-32.9° (c=5)

SMILES

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CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O

InChI

InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1

InChIKey

MRMBZHPJVKCOMA-YJFSRANCSA-N

LogP

-1.95710

Complexity

609

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

CHEBI:3089
CCG-268031
L-627
BIAPENEM [INN]
CHEMBL285347
6-(((4R,5S,6S)-2-CARBOXY-6-((1R)-1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-EN-3-YL)THIO)-6,7-DIHYDRO-5H-PYRAZOLO(1,2-A)(1,2,4)TRIAZOL-4-IUM INNER SALT
DB13028
A804499
Biapenem [USAN:INN]
EX-A4945
(4R,5S,6S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
CL 186815
BIAPENEM [WHO-DD]
CLI 86815
6-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium Inner Salt
(4R,5S,6S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylthio)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
LJ-C10627
LJC10627
NCGC00164551-02
Biapenern
s1370
D01057
L 627
Omegacin (TN)
AKOS025149478
NCGC00164551-05
Biapenem (JAN/USAN/INN)
Biapenem, >=98% (HPLC)
120410-24-4
UNII-YR5U3L9ZH1
CL 186,815

MDL Number

MFCD00864863

FAQ

What is Biapenem (CAS: 120410-24-4)?

Biapenem is a synthetic broad-spectrum antibiotic belonging to the carbapenem class. It has the chemical formula C16H21N3O4S and is known for its stability in acidic environments. This compound is effective against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable option in antimicrobial therapy.

What are the main uses of Biapenem (CAS: 120410-24-4)?

Biapenem is primarily used in the treatment of severe bacterial infections, including those affecting the respiratory tract, urinary tract, and skin. It is also utilized in research for studying bacterial resistance and in pharmaceutical development as a potential therapeutic agent. Its broad-spectrum activity makes it useful in clinical settings where multidrug-resistant pathogens are present.

Is Biapenem (CAS: 120410-24-4) safe?

Biapenem is generally considered safe when used as directed, but it should be handled with care to avoid skin contact and inhalation. Safety data indicate that it has low toxicity, though proper protective equipment is recommended during handling. It is subject to standard pharmaceutical safety regulations to ensure its use in medical and research contexts is appropriate and controlled.

How should Biapenem (CAS: 120410-24-4) be stored?

Biapenem should be stored in a cool, dry place away from direct light. It is typically kept at a temperature range of 2-8°C and requires protection from moisture. Proper storage ensures its stability and effectiveness, and it should be kept in a sealed, airtight container to prevent degradation.