Clopidogrel hydrogen sulfate

Basic Information

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CAS Number

120202-66-6

Molecular Formula

C16H18ClNO6S2

Molecular Weight

419.91 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

178-184°C

Boiling Point

447.3°C at 760 mmHg

Solubility

DMSO: ~26 mg/mL

Specific Rotation

+54° - +70° (c=0.5, MeOH)

SMILES

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COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.OS(=O)(=O)O

InChI

InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1

InChIKey

FDEODCTUSIWGLK-RSAXXLAASA-N

LogP

3.0211000000000006

Topological Polar Surface Area

104.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

463

Safety Information

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GHS Hazard Pictograms

H303

Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

Hazard Class

Class 8 Class 8

Sensitiveness

thermally sensitive

Synonyms & References

English

Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate, sulfate (1:1)
CLOPIDOGREL BISULFATE COMPONENT OF DUOCOVER
Methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)acetate monosulfate
D00769
(S)-(+)-Clopidogrel hydrogensulfate, >=98% (HPLC)
(S)-(+)-Clopidogrel bisulfate;(S)-(+)-Clopidogrel hydrogen sulfate
HY-17459
Clopidogrel sulphate
Clopidogrel Bisulfate [USAN]
THIENO(3,2-C)PYRIDINE-5(4H)-ACETIC ACID, .ALPHA.-(2-CHLOROPHENYL)-6,7-DIHYDRO-, METHYL ESTER, (S)-, SULPHATE (1:1)
(s)-(+)-clopidogrel bisulfate
Clopidogrel bisulphate
CLOPIDOGREL/ACETYLSALICYCLIC ACID TEVA COMPONENT CLOPIDOGREL BISULFATE
methyl(S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetatesulfate
Clopidogrel bisulfate (USAN:USP)
Clopidogrel bisulfate, United States Pharmacopeia (USP) Reference Standard
SCHEMBL33556
FDEODCTUSIWGLK-RSAXXLAASA-N
CLOPIDOGREL BISULFATE (MART.)
(+) Clopidogrel Bisulfate
Clopidogrel hydrogen sulfate, European Pharmacopoeia (EP) Reference Standard
Clopidogrel for system suitability, European Pharmacopoeia (EP) Reference Standard
bisulfato de clopidogrel
(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate
CLOPIDOGREL BISULFATE (USP-RS)
J-006637
Thieno(3,2-c)pyridine-5(4H)-acetic acid, alpha-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (alphaS)-, sulfate (1:1)
111GE004
methyl (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
CLOPIDOGREL BISULFATE [VANDF]
METHYL (+)-(S)-.ALPHA.-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO(3,2-C)PYRIDINE-5(4H)-ACETATE, SULFATE (1:1)

MDL Number

MFCD00876395

Customs Code

2942000000

FAQ

What is Clopidogrel hydrogen sulfate (CAS: 120202-66-6)?

Clopidogrel hydrogen sulfate (CAS: 120202-66-6) is a pharmaceutical compound used as an antiplatelet agent. Its chemical formula is C16H16N2O2S·H2SO4, and it is a white to off-white powder with good solubility in water. It functions as a prodrug, converting to active metabolites that inhibit platelet aggregation, making it vital in cardiovascular disease management.

What are the main uses of Clopidogrel hydrogen sulfate (CAS: 120202-66-6)?

Clopidogrel hydrogen sulfate (CAS: 120202-66-6) is primarily used in pharmaceuticals to treat and prevent thrombotic events like heart attacks and strokes. It is also employed in research for drug development and as an intermediate in industrial chemical syntheses. Its antiplatelet properties make it a key component in cardiovascular therapy.

Is Clopidogrel hydrogen sulfate (CAS: 120202-66-6) safe?

Clopidogrel hydrogen sulfate (CAS: 120202-66-6) is generally safe when used as directed, but it may cause side effects such as bleeding risks. Handling precautions include wearing gloves and avoiding eye contact. It meets safety standards for pharmaceutical use, with regulatory approval from the FDA and other agencies for prescribed medical applications.

How should Clopidogrel hydrogen sulfate (CAS: 120202-66-6) be stored?

Clopidogrel hydrogen sulfate (CAS: 120202-66-6) should be stored in a cool, dry place below 25°C, away from light. Maintain low humidity and use airtight, light-resistant containers. Keep it in a secure location to prevent contamination or misuse, ensuring stability and efficacy of the compound.