Ethyl (3-bromo-4-methylphenyl)acetate | CAS No. 1201633-86-4

Ethyl (3-bromo-4-methylphenyl)acetate

Basic Information

CAS Number

1201633-86-4

Molecular Formula

C11H13BrO2

Molecular Weight

257.13 g/mol

AD

Basic Physical Properties

CCOC(=O)Cc1ccc(c(c1)Br)C

InChI

InChI=1S/C11H13BrO2/c1-3-14-11(13)7-9-5-4-8(2)10(12)6-9/h4-6H,3,7H2,1-2H3

InChIKey

YNYLPGRUDFNAQO-UHFFFAOYSA-N

LogP

2.863120000000001

Topological Polar Surface Area

26.3 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

194

Synonyms & References

English

  • ethyl 2-(3-bromo-4-methylphenyl)acetate
  • Ethyl 3-bromo-4-methylphenylacetate
  • 2-bromo-p-tolylacetic acid ethyl ester
  • (3-Bromo-4-methylphenyl)acetic acid ethyl ester

MDL Number

MFCD03427895

FAQ

What are the physical and chemical properties of Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4)?

Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4) is a crystalline compound with a molecular weight of approximately 275.04 g/mol. It has a low solubility in water but is soluble in many organic solvents. Chemically, it is relatively stable but can undergo nucleophilic substitution reactions, particularly with strong bases. It has a melting point of around 45-47°C and a boiling point of approximately 215°C.

How is Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4) typically synthesized?

Ethyl (3-bromo-4-methylphenyl)acetate is typically synthesized via the acetylation of 3-bromo-4-methylphenol. The reaction proceeds via a nucleophilic acyl substitution, where an acetyl group is introduced to the bromo-substituted phenol. The process often involves the use of an acetic anhydride and a base such as pyridine as a catalyst to improve the reaction selectivity and yield.

What industries use Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4)?

Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4) is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also used in the polymer industry as a monomer or modifier. Additionally, it finds applications in the production of sensors and electronics due to its chemical stability and reactivity.

What precautions should be taken when handling Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4)?

When handling Ethyl (3-bromo-4-methylphenyl)acetate (CAS: 1201633-86-4), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. This compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be handled according to the manufacturer’s safety data sheet (SDS). Proper storage should be in a cool, dry place, away from sources of heat and ignition. Always refer to the latest SDS for detailed safety information.

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