2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) | CAS No. 120011-70-3

2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1)

Basic Information

CAS Number

120011-70-3

Molecular Formula

C24H30ClNO3

Molecular Weight

415.96 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

223-227°C

COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl

InChI

InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

InChIKey

XWAIAVWHZJNZQQ-UHFFFAOYSA-N

LogP

4.782900000000004

Topological Polar Surface Area

38.769999999999996 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

510

Safety Information

View Safety Information

GHS Hazard Pictograms

H300H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

  • E2020;E-2020
  • Donepezil HCl (Aricept)
  • BCP02205
  • CCG-213309
  • BNAG
  • 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride
  • NCGC00167537-02
  • donepezilhcl
  • Donepezil, HCl
  • Donepezil Hyrochloride5mg
  • DONEPEZIL HYDROCHLORIDE [MI]
  • MLS000758276
  • DTXSID0046698
  • 2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride
  • Memac
  • NSC758882
  • DONEPEZIL HYDROCHLORIDE [USP MONOGRAPH]
  • NC00293
  • DONEPEZIL HYDROCHLORIDE [JAN]
  • Donepezil hydrochloride [USAN]
  • 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-, hydrochloride
  • Q-100096
  • rac-1-benzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidinium chloride
  • DONEPEZIL HYDROCHLORIDE (EP MONOGRAPH)
  • Donepezil hydrochloride,(S)
  • AKOS000277343
  • (+-)-2,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride
  • ADLARITY
  • donepezil hydrochloride hydrate
  • DONEPEZIL HYDROCHLORIDE [EP MONOGRAPH]
  • 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-1H-inden-1-one

MDL Number

MFCD00881312

Customs Code

2933399090

FAQ

What is 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) (CAS: 120011-70-3)?

2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) is a chemical compound with the CAS number 120011-70-3. It is a hydrochloride salt of a piperidine derivative, featuring a benzyl group, two methoxy groups, and an indanone ring. This compound is known for its complex structure and is often used in medicinal chemistry research due to its potential pharmacological properties.

What are the main uses of 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) (CAS: 120011-70-3)?

The primary use of 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) is in pharmaceutical research, particularly for the development of drugs targeting central nervous system disorders. It may also find applications in organic synthesis and as a precursor in the formulation of various therapeutic agents. Its chemical structure makes it relevant for studies involving receptor modulation and drug design.

Is 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) (CAS: 120011-70-3) safe?

The safety of 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) depends on its application and exposure conditions. As a research chemical, it is generally handled in controlled laboratory environments. Precautions include wearing protective gear such as gloves and goggles, and ensuring proper ventilation. Safety standards for handling should follow guidelines for handling organic compounds and hazardous materials.

How should 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) (CAS: 120011-70-3) be stored?

2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It should be kept in a sealed container to prevent moisture ingress and contamination. Avoid exposure to air and light to maintain its stability and potency. Storage conditions should comply with standard chemical safety and handling protocols.

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