1-Methylpyrrolidine

Basic Information

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CAS Number

120-94-5

Molecular Formula

C5H11N

Molecular Weight

85.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

-90 ºC

Boiling Point

80-81 °C

Water Solubility

fully miscible

Solubility

213g/l

Refractive Index

n20/D 1.425

Vapor Pressure

79.6±0.1 mmHg at 25°C

SMILES

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CN1CCCC1

InChI

InChI=1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3

InChIKey

AVFZOVWCLRSYKC-UHFFFAOYSA-N

LogP

0.712

pKa

10.32(at 25℃)

Topological Polar Surface Area

3.24 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

37.2

Safety Information

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GHS Hazard Pictograms

H225

H302

H314

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 3 Class 3

Sensitiveness

Sensitive to air

Explosive Limit

1.1-9.1%(V)

Synonyms & References

English

1-Methylpyrrolidine
N-Methylpyrrolidine
1-methyl
1-methyl-pyrrolidin
1-methyl-pyrrolidine
Methylpyrrolidine
N-methyl-pyrrolidine
Pyrrolidine,1-methyl
Pyrrolidine,l-methyl
Pyrrolidine,N-methyl
NSC 65579
1-Methylpyrrodine
cefepiMe iMpurity G
Cefepime Impurity 1
Pyrrolidine,l-methyl-
N-METHYLPYRROLIDINE
1-METHYLPYRROLIDINE
1-methylpyrrolidine

MDL Number

MFCD00003173

Customs Code

2921300090

FAQ

What is 1-Methylpyrrolidine (CAS: 120-94-5)?

1-Methylpyrrolidine is a cyclic secondary amine with the chemical formula C5H11N. It is a colorless liquid with a mild, pleasant odor and is commonly used as a building block in organic synthesis. This compound is known for its solubility in organic solvents and its ability to act as a hydrogen bond donor and acceptor, which makes it valuable in various chemical applications.

What are the main uses of 1-Methylpyrrolidine (CAS: 120-94-5)?

1-Methylpyrrolidine is widely used in pharmaceuticals as a chiral auxiliary and in the synthesis of drugs. It also finds applications in the fragrance industry, polymer science, and as a solvent in chemical research. Its versatility makes it an important intermediate in the production of agrochemicals and specialty chemicals.

Is 1-Methylpyrrolidine (CAS: 120-94-5) safe?

1-Methylpyrrolidine is generally considered safe when handled properly, but it may cause skin and eye irritation. It is advisable to use personal protective equipment (PPE) such as gloves and goggles. Safety data sheets (SDS) should be consulted for proper handling and disposal guidelines to ensure compliance with occupational and environmental safety standards.

How should 1-Methylpyrrolidine (CAS: 120-94-5) be stored?

1-Methylpyrrolidine should be stored in a cool, dry, and well-ventilated area away from light. It is typically kept in a sealed, non-reactive container such as a glass or stainless steel bottle. Storage at temperatures below 25°C is recommended to maintain stability and prevent degradation.