2-Amino-4-(2-methyl-2-propanyl)phenol

Basic Information

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CAS Number

1199-46-8

Molecular Formula

C10H15NO

Molecular Weight

165.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

158.0 to 164.0 deg-C

Boiling Point

293.09°C (rough estimate)

Flash Point

120.1℃

Refractive Index

1.5290 (estimate)

SMILES

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CC(C)(C)C1=CC(=C(C=C1)O)N

InChI

InChI=1S/C10H15NO/c1-10(2,3)7-4-5-9(12)8(11)6-7/h4-6,12H,11H2,1-3H3

InChIKey

RPJUVNYXHUCRMG-UHFFFAOYSA-N

LogP

2.2719000000000005

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

150

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

EINECS 214-844-4
PHENOL, 2-AMINO-4-TERT-BUTYL-
SR-01000001492-2
NCGC00023894-03
2-azanyl-4-tert-butyl-phenol
2-Amino-4-tert-butyl-phenol
AKOS000111158
Oprea1_128902
SR-01000001492
Q27254243
DTXSID60152615
2-Amino-4-tert-butylphenol
InChI=1/C10H15NO/c1-10(2,3)7-4-5-9(12)8(11)6-7/h4-6,12H,11H2,1-3H
HMS1474O17
SY018795
MFCD00007698
SMR000034103
5-TERT-BUTYL-2-HYDROXYANILINE
o-Amino-p-tert-butylphenol
2-Hydroxy-5-tert-butylaniline
A804398
Phenol, 2-amino-4-(1,1-dimethylethyl)-
A0957
ChemDiv3_000677
FT-0611267
AC1524
Q-200232
NS00023892
1199-46-8
p-tert-butyl-o-aminophenol
SCHEMBL621595

MDL Number

MFCD00007698

Customs Code

2922299090

FAQ

What is 2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8)?

2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) is a substituted phenol with the chemical formula C9H15NO2. It features an amino group at the 2-position and a tert-butyl group at the 4-position on a benzene ring. This compound is known for its aromatic structure and hydroxyl functionality, making it a key intermediate in organic synthesis. Its properties include solubility in polar solvents and a characteristic pungent odor.

What are the main uses of 2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8)?

2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) is widely used in pharmaceuticals as a building block for drug development, particularly in antifungal and anti-inflammatory compounds. It also serves in industrial applications for producing dyes and agrochemicals. In research, it is employed as a precursor for synthesizing complex organic molecules. Its versatility stems from the reactivity of the amino and hydroxyl groups.

Is 2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) safe?

2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation of its vapors could be harmful. Safety standards recommend using appropriate personal protective equipment (PPE) and following OSHA guidelines. Proper storage and ventilation are essential to minimize risks during use.

How should 2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) be stored?

2-Amino-4-(2-methyl-2-propanyl)phenol (CAS: 1199-46-8) should be stored in a sealed, airtight container in a cool (below 25°C), dry, and dark environment to maintain stability. It is sensitive to moisture and light, which can degrade its quality. Storage in a well-ventilated area is advised, and it should be kept away from incompatible substances to ensure safety and longevity.