PF-3845 | CAS No. 1196109-52-0

PF-3845

Basic Information

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CAS Number

1196109-52-0

Molecular Formula

C24H23F3N4O2

Molecular Weight

456.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

DMSO: ≥45mg/mL

SMILES

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O=C(N1CCC(CC1)Cc1cccc(c1)Oc1ccc(cn1)C(F)(F)F)Nc1cccnc1

InChI

InChI=1S/C24H23F3N4O2/c25-24(26,27)19-6-7-22(29-15-19)33-21-5-1-3-18(14-21)13-17-8-11-31(12-9-17)23(32)30-20-4-2-10-28-16-20/h1-7,10,14-17H,8-9,11-13H2,(H,30,32)

InChIKey

NBOJHRYUGLRASX-UHFFFAOYSA-N

LogP

5.774300000000005

Topological Polar Surface Area

67.35000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Synonyms & References

English

PF 3845
N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide
PF-3845
N-3-pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-Piperidinecarboxamide
,PF3845,PF 3845
4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)benzyl)-N-(pyridin-3-yl)piperidine-1-carboxamide
PF 3845 hydrate
N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide hydrate

MDL Number

MFCD18382105

FAQ

What is PF-3845 (CAS: 1196109-52-0)?

PF-3845 is a small organic molecule used primarily in cancer research as a selective inhibitor of mammalian Ste20-like kinase 1 (MST1) and 2 (MST2). It is a colorless to pale yellow oil with a molecular formula of C15H14N4O5 and a CAS number of 1196109-52-0.

What are the main uses of PF-3845 (CAS: 1196109-52-0)?

PF-3845 is predominantly used in research, particularly in cell biology and cancer studies. It is effective in inhibiting MST1 and MST2 kinases, which are involved in cellular processes such as cell growth and apoptosis. This makes it useful for studying these kinases and their roles in various diseases.

Is PF-3845 (CAS: 1196109-52-0) safe?

PF-3845 is generally safe when handled with proper protective measures. It should be stored away from direct sunlight and protected from moisture. Users should wear gloves and appropriate personal protective equipment when handling the compound to prevent skin contact. Ingestion or inhalation should be avoided to ensure safety.

How should PF-3845 (CAS: 1196109-52-0) be stored?

PF-3845 should be stored in a tightly sealed container at a temperature below 30°C and away from direct sunlight. It should be kept in a cool, dry place and protected from moisture. Any exposed surfaces should be wiped clean with a dry cloth. Proper labeling and container sealing are essential to prevent contamination and ensure safety during storage.