(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine | CAS No. 119356-77-3

(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine

Basic Information

CAS Number

119356-77-3

Molecular Formula

C21H23NO

Molecular Weight

305.42 g/mol

AD

Basic Physical Properties

Boiling Point

454.4°C at 760 mmHg

Density

1.081

Flash Point

132.6°C

Refractive Index

1.607

CN(C)[C@@H](CCOc1cccc2c1cccc2)c3ccccc3

InChI

InChI=1S/C21H23NO/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21/h3-14,20H,15-16H2,1-2H3/t20-/m0/s1

InChIKey

USRHYDPUVLEVMC-FQEVSTJZSA-N

LogP

4.911600000000004

Topological Polar Surface Area

12.47 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

337

Synonyms & References

English

  • (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine
  • (aS)-N,N-Dimethyl-a-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine
  • (S)-(+)--N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine
  • (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine
  • (S)-(+)-Dapoxetine
  • Dapoxetine
  • Dapoxetine (free base)
  • Dapoxetine hydrochloride
  • S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
  • Dapoxetina
  • Dapoxetinum
  • Priligy
  • (S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
  • DAPOXETIN
  • Detoxetine
  • Dapoxetine base
  • D-Dapoxetine HCL
  • Dapoxetine-d7 HCl
  • apoxetine hydrochloride
  • Dapoxetine [INN]
  • Dapoxetinum [INN-Latin]
  • Dapoxetina [INN-Spanish]
  • LY 210448
  • GB2433A4M3
  • Benzenemethanamine, N,N-dimethyl-alpha-(2-(1-naphthalenyloxy)ethyl)-, (+)-
  • (+)-Dapoxetine
  • (1s)-n,n-dimethyl-3-(1-naphthyloxy)-1-phenylpropan-1-amine
  • Kutub, Priligy, Duratia
  • DSSTox_RI
  • (S)-Dapoxetine
  • DSSTox_RID_97302

MDL Number

MFCD00865355

FAQ

What is (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3)?

(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) is a chiral organic compound with the chemical formula C21H23NO. It features a naphthyl group, a phenyl group, and a propanamine backbone with two methyl substituents. This compound is known for its potential pharmacological activity and is often studied in chemical research for its biological properties and applications.

What are the main uses of (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3)?

(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) is primarily used in pharmaceutical research as a potential serotonin receptor agonist. It may also serve as a lead compound for drug development targeting neurological disorders. Additionally, it is utilized in chemical synthesis and as a reference material in organic chemistry studies.

Is (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) safe?

Safety of (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) depends on exposure conditions. While it is not classified as highly toxic, it requires proper handling to avoid skin or eye contact. Protective equipment, such as gloves and goggles, is recommended. Always follow safety guidelines for chemical exposure and storage to minimize risks.

How should (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) be stored?

(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine (CAS: 119356-77-3) should be stored in a cool, dry place away from light. Maintain storage conditions at 2-8°C and ensure humidity levels are low. Keep the compound in a sealed, airtight container made of glass or plastic to preserve stability and prevent contamination.

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