Framycetin | CAS No. 119-04-0

Framycetin

Basic Information

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CAS Number

119-04-0

Molecular Formula

C23H46N6O13

Molecular Weight

614.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

658.4°C (rough estimate)

Refractive Index

1.6000 (estimate)

SMILES

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C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N

InChI

InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1

InChIKey

PGBHMTALBVVCIT-VCIWKGPPSA-N

LogP

-8.895300000000017

Topological Polar Surface Area

353.11 Å²

Hydrogen Bond Donor/Acceptor

19 / 19

Complexity

872

Synonyms & References

English

HY-17624
Q4492348
Fradiomycin
BRN 0101621
D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy
Fradiomycin B
FRAMYCETIN [WHO-DD]
Soframycin
AKOS024284361
NEOMYCIN SULFATE
J-004060
Francetin
6-(2-{(4S,2R,3R,5R)-4-[(5S,6S,2R,3R,4R)-3-amino-6-(aminomethyl)-4,5-dihydroxy( 2H-3,4,5,6-tetrahydropyran-2-yloxy)]-3-hydroxy-5-(hydroxymethyl)oxolan-2-yloxy }(3S,6S,1R,2R,4R)-4,6-diamino-3-hydroxycyclohexyloxy)(3S,2R,4R,5R,6R)-5-amino- 2-(aminomethyl)-2H
Nivemycin
Dekamycin iii
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
Framycetinum [INN-Latin]
Neomycine
Neomcin
DB00452
D05140
Antibiotique
Neomicina
Mycifradin
CS-6390
Framygen
HMS2089P15
BRD-K71013094-065-01-2
NEOMYCIN B
Antibiotic produced by Streptomyces decaris. Neomycin B
CCRIS 5462

MDL Number

MFCD09788228

FAQ

What regulatory guidelines apply to Framycetin (CAS: 119-04-0)?

Framycetin (CAS: 119-04-0) is regulated under the GHS (Global Harmonized System of Classification and Labeling of Chemicals) for hazardous communication. It falls under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the European Union, requiring manufacturers and importers to register substances if they are manufactured or imported in quantities greater than 1 tonne annually. In the United States, FDA and EPA have specific labeling and handling requirements due to its potential toxicity.

Are there alternatives to Framycetin (CAS: 119-04-0) in synthesis?

Framycetin (CAS: 119-04-0) is an antibiotic, and alternatives include other antibiotics such as polymyxin B, colistin, and tigecycline. Isomers and analogs like framycetin sulfate can also be considered. Common alternative reagents in its synthesis include amino acids, sugars, and other organic compounds depending on the specific synthesis route.

What is the market or research trend for Framycetin (CAS: 119-04-0)?

The market for Framycetin (CAS: 119-04-0) has shown stability, but research trends are shifting towards understanding its mechanisms of action and exploring its potential in combination therapies. Recent studies focus on its effectiveness against multidrug-resistant pathogens. Market trends indicate growing interest in antimicrobial research, driven by the increasing prevalence of drug-resistant infections.

How should waste containing Framycetin (CAS: 119-04-0) be handled?

Waste containing Framycetin (CAS: 119-04-0) should be collected in appropriate containers and labeled as hazardous. Incineration is a common method for waste disposal, but professional waste disposal services should be used. Environmental protection measures should include proper storage and handling to prevent leaks, with precautionary measures to avoid exposure to the environment. Compliance with local, national, and international regulations is essential.