4-chloro-1H-pyrrolo[2,3-c]pyridine

Basic Information

View in Editor

CAS Number

1188313-15-6

Molecular Formula

C7H5ClN2

Molecular Weight

152.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=CNC2=CN=CC(=C21)Cl

InChI

InChI=1S/C7H5ClN2/c8-6-3-9-4-7-5(6)1-2-10-7/h1-4,10H

InChIKey

UMYWTYDKYPYCGX-UHFFFAOYSA-N

LogP

2.2162999999999995

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

129

Synonyms & References

English

4-Chloro-1H-pyrrolo[2,3-c]pyridine
1H-Pyrrolo[2,3-C]pyridine, 4-chloro-
4-Chloro-1H-pyrrolo(2,3-C)pyridine
4-CHLORO-6-AZAINDOLE
HIN1637
WT1428
3182AA
FCH1172315
PB15239
RP08986
4-chloranyl-1H-pyrrolo[2,3-c]pyridine
ST1271484
AX8218441
AB0094154
AM20050699
A804115
4-chloro-1H-pyrrolo[2,3-c]pyridine
DB-061426
SCHEMBL1019760
AS-82139
MFCD16657181
AKOS015949548
SY034850
DTXSID40676829
J-514891
W-205023
1188313-15-6
CS-0020014

MDL Number

MFCD16657181

FAQ

What are the physical and chemical properties of 4-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 1188313-15-6)?

4-Chloro-1H-pyrrolo[2,3-c]pyridine is a solid at room temperature with a high melting point. Its molecular weight is approximately 189.02 g/mol. This compound is poorly soluble in water but soluble in organic solvents like dichloromethane and acetonitrile. It is chemically stable but can react with strong bases and oxidizing agents.

How is 4-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 1188313-15-6) typically synthesized?

4-Chloro-1H-pyrrolo[2,3-c]pyridine is commonly synthesized via the reaction of 1H-pyrrolo[2,3-c]pyridine with thionyl chloride in the presence of a catalyst. The yield is typically around 85-90%, and the method is selective and efficient.

What industries use 4-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 1188313-15-6)?

4-Chloro-1H-pyrrolo[2,3-c]pyridine is used in the pharmaceutical industry for the synthesis of novel drugs. It is also utilized in the development of sensors and as a precursor in the production of materials for semiconductors and polymers.

What precautions should be taken when handling 4-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 1188313-15-6)?

When handling 4-chloro-1H-pyrrolo[2,3-c]pyridine, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store it in a fume hood to minimize exposure. In case of a spill, immediately clean up using standard procedures and follow the Material Safety Data Sheet (MSDS) for detailed instructions.