5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde | CAS No. 1188037-01-5

5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

Basic Information

CAS Number

1188037-01-5

Molecular Formula

C17H13BrN2O2

Molecular Weight

357.21 g/mol

AD

Basic Physical Properties

COc1ccc(cc1)c2c(c(n(n2)c3ccccc3)Br)C=O

InChI

InChI=1S/C17H13BrN2O2/c1-22-14-9-7-12(8-10-14)16-15(11-21)17(18)20(19-16)13-5-3-2-4-6-13/h2-11H,1H3

InChIKey

OEMWMRNELHHBMB-UHFFFAOYSA-N

LogP

4.122900000000002

Topological Polar Surface Area

44.120000000000005 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

368

Synonyms & References

English

  • 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
  • "1H-Pyrazole-4-carboxaldehyde, 5-bromo-3-(4-methoxyphenyl)-1-phenyl-
  • 1H-Pyrazole-4-carboxaldehyde, 5-bromo-3-(4-methoxyphenyl)-1-phenyl-
  • 5-bromo-3-(4-methoxyphenyl)-1-phenyl-1H-Pyrazole-4-carboxaldehyde
  • C17H13BrN2O2
  • PubChem23648
  • 3143AA
  • BC004953
  • ST2406118
  • AX8221884
  • 5-bromo-3-(4-methoxyphenyl)-1-phenylpyrazole-4-carbaldehyde
  • 5-Bromo-3-(4-methoxy-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

MDL Number

MFCD09746343

FAQ

What are the physical and chemical properties of 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS: 1188037-01-5)?

5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde is a crystalline compound with a molecular weight of approximately 378.08 g/mol. It has a melting point of 195-197°C and is slightly soluble in ethanol and acetone. The compound is known for its reactivity in electrophilic aromatic substitution reactions and nucleophilic addition reactions.

How is 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS: 1188037-01-5) typically synthesized?

5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde can be synthesized via the condensation of 2-bromo-4-methoxyphenylacetaldehyde with 1-phenyl-3H-pyrazol-5(4H)-one. The synthesis typically involves the use of a catalyst and proceeds with good yield, with the product isolated by recrystallization from an appropriate solvent.

What industries use 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS: 1188037-01-5)?

5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde finds applications in the pharmaceutical industry for the development of new drugs, particularly as an intermediate in the synthesis of biologically active compounds. It also has potential uses in the polymer industry for the modification of polymers and in the semiconductor industry for the production of electronic materials.

What precautions should be taken when handling 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS: 1188037-01-5)?

When handling 5-Bromo-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbents and disposed of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

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