N-Acetyl-L-(-)-leucine

Basic Information

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CAS Number

1188-21-2

Molecular Formula

C8H15NO3

Molecular Weight

173.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

187-190 °C

Boiling Point

369.7°C at 760 mmHg

Water Solubility

0.81 g/100 mL (20 ºC)

Flash Point

177.4℃

Refractive Index

-22 ° (C=5, EtOH)

Vapor Pressure

0.0±1.8 mmHg at 25°C

Specific Rotation

-24.5 º (c=4, MeOH)

SMILES

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CC(C)CC(C(=O)O)NC(=O)C

InChI

InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1

InChIKey

WXNXCEHXYPACJF-ZETCQYMHSA-N

LogP

0.6218000000000001

Topological Polar Surface Area

66.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

177

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1188-21-2
NS00014888
ACETYLLEUCINE, L-
NCGC00016567-01
HMS501P04
L-Leucine, N-acetyl-
N-Acetyl-L-leucine, ReagentPlus(R), 99%
SBI-0051693.P002
Spectrum_001313
KBioSS_001793
Tox21_111362_1
(S)-2-Acetamido-4-methylpentanoic acid
HMS548M13
A0098
BRD-K27406233-001-05-1
HY-59291
SPECTRUM1502001
E915HL7K2O
NINDS_000622
Prestwick2_000896
KBioGR_000471
AM20080126
KBio1_000622
BPBio1_000784
SPBio_002921
Spectrum3_001480
AB00513952
Prestwick3_000896
NCGC00094935-01
Z756438860
NSC-206316

MDL Number

MFCD00065131

Customs Code

2924199090

FAQ

What is N-Acetyl-L-(-)-leucine (CAS: 1188-21-2)?

N-Acetyl-L-(-)-leucine is an acetylated derivative of the amino acid leucine, with the CAS number 1188-21-2. It is a white crystalline solid that is soluble in water and commonly used in chemical research. This compound exhibits optical activity and is often employed as a building block in the synthesis of other pharmaceutical compounds.

What are the main uses of N-Acetyl-L-(-)-leucine (CAS: 1188-21-2)?

N-Acetyl-L-(-)-leucine is primarily used in pharmaceutical research for the development of drugs and as a chiral intermediate. It also finds applications in the synthesis of amino acid derivatives and in biochemical studies. Its utility stems from its structural versatility and optical purity, making it valuable in various scientific and industrial contexts.

Is N-Acetyl-L-(-)-leucine (CAS: 1188-21-2) safe?

N-Acetyl-L-(-)-leucine is generally considered safe when handled properly. It has low toxicity, but as with any chemical, it is important to follow standard safety protocols, such as wearing gloves and goggles. It should be stored in a well-ventilated area and kept away from incompatible substances to ensure safe handling and use.

How should N-Acetyl-L-(-)-leucine (CAS: 1188-21-2) be stored?

N-Acetyl-L-(-)-leucine should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It is best kept in a sealed container to prevent moisture absorption and contamination. Avoid exposure to heat, light, and air to maintain its stability and quality over time.