Tazarotene | CAS No. 118292-40-3

Tazarotene

Basic Information

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CAS Number

118292-40-3

Molecular Formula

C21H21NO2S

Molecular Weight

165.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

102.0 to 106.0 deg-C

Boiling Point

499.8°C at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

256.1±28.7 °C

Solubility

DMSO: >15mg/mL

Vapor Pressure

0.0±1.3 mmHg at 25°C

SMILES

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CCOC(=O)c1ccc(nc1)C#Cc1ccc2c(c1)C(C)(C)CCS2

InChI

InChI=1S/C9H11NO2/c1-3-12-9(11)8-5-4-7(2)10-6-8/h4-6H,3H2,1-2H3

InChIKey

FEWVINDUUUHRKM-UHFFFAOYSA-N

LogP

1.5667200000000001

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

547

Safety Information

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GHS Hazard Pictograms

H316

Hazard Statement

H316 Causes mild skin irritation
Skin corrosion/irritation

Synonyms & References

English

Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
TAZAROTENE
agn190168
6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-pyridinecarboxylic Acid Ethyl Ester
Tazorac
Zorac
6-[(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran)-6-yl]nicotinic acid ethyl ester
ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate
6-[(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic acid ethyl ester
AGN-190168
ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl] nicotinate
Ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]pyridine-3-carboxylate
Avage
Tazarotene(Avage)
Fabior
Tazarotene [USAN:INN]
AGN 190168
Tazarotene (Avage)
Zora
C21H21NO2S
81BDR9Y8PS
OGQICQVSFDPSEI-UHFFFAOYSA-N
3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester
ethyl 6-(2-(4,4-dimethylthiochroman-6-yl)et
Tazorac/zorac
Tazarotene, >=98%
Tazarotene 99% Min
Tazarotene
ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate

MDL Number

MFCD00867628

Customs Code

2942000000

FAQ

What is Tazarotene (CAS: 118292-40-3)?

Tazarotene is a synthetic retinoid with the chemical formula C20H24O3. It is known for its ability to modulate skin cell growth and differentiation. Tazarotene is a derivative of tricyclic retinoid acid and is commonly used in dermatological treatments due to its topical application properties.

What are the main uses of Tazarotene (CAS: 118292-40-3)?

Tazarotene is primarily used in the treatment of psoriasis and acne. It works by reducing the production of skin cells and preventing the formation of comedones. Additionally, it is employed in research for studying skin disorders and in pharmaceutical development for topical therapies.

Is Tazarotene (CAS: 118292-40-3) safe?

Tazarotene is generally considered safe when used as directed, but it can cause skin irritation and sensitivity to light. Proper handling, such as using gloves and avoiding contact with eyes, is recommended. Safety standards ensure its controlled use in medical and research settings to minimize adverse effects.

How should Tazarotene (CAS: 118292-40-3) be stored?

Tazarotene should be stored in a cool, dry place away from light. It is typically kept in airtight containers at a temperature below 25°C. Maintaining low humidity and avoiding exposure to moisture is essential to preserve its stability and effectiveness over time.