[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid)

Basic Information

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CAS Number

118072-93-8

Molecular Formula

C5H10N2O7P2

Molecular Weight

272.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

193-2040C (dec)

Boiling Point

764°C at 760 mmHg

Density

2.13

Flash Point

415.8°C

SMILES

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OC(Cn1ccnc1)(P(=O)(O)O)P(=O)(O)O

InChI

InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)

InChIKey

XRASPMIURGNCCH-UHFFFAOYSA-N

LogP

-1.1154000000000002

Topological Polar Surface Area

153.10999999999999 Å²

Hydrogen Bond Donor/Acceptor

5 / 9

Complexity

327

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonic acid
Zoledronic acid hydrate
ZOLEDRONATE
[1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene]bisphosphonic acid
2-(Imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic Acid
CGP-4244
Zoledronic acid
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate
CGP 42446
CGP42446A
P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrate
ZOL 446
Zoledronic acid monohydrate
Zometa,Zomera,Aclasta and Reclast
Orazol
BPH 91
ZoMeta
Aclasta
Reclast
CGP-42446
Zoledronic
(1-Hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid
Zomera
ZOL
Aclasta and Reclast
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
Zometa (TN)
Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-
70HZ18PH24
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
Zoledronic Acid

MDL Number

MFCD00867791

FAQ

What is [1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8)?

[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid), with CAS number 118072-93-8, is a bisphosphonic acid derivative that contains an imidazole ring. Its chemical formula is C8H16N2O8P2. It is known for its strong acidic properties and is often used in chemical synthesis and research due to its versatile functional groups.

What are the main uses of [1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8)?

[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8) is primarily used in pharmaceutical research as a potential chelating agent and in the synthesis of organic compounds. It also finds applications in industrial processes involving metal ion binding and in the development of new materials due to its phosphonic acid functionality.

Is [1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8) safe?

[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8) is generally considered safe when handled properly. However, it should be used with caution, as it may cause irritation to the skin and eyes. Protective measures such as gloves, goggles, and a well-ventilated area are recommended to ensure safe handling and compliance with safety standards.

How should [1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8) be stored?

[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) (CAS: 118072-93-8) should be stored in a cool, dry place away from light. It is best kept in a sealed, airtight container to maintain its stability. Storage should also ensure that it is kept out of reach of children and not exposed to incompatible substances.