Abemaciclib Impurity 16

Basic Information

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CAS Number

1180132-17-5

Molecular Formula

C12H20N4

Molecular Weight

220.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

362 ºC

Flash Point

173 ºC

SMILES

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CCN1CCN(CC1)Cc2ccc(nc2)N

InChI

InChI=1S/C12H20N4/c1-2-15-5-7-16(8-6-15)10-11-3-4-12(13)14-9-11/h3-4,9H,2,5-8,10H2,1H3,(H2,13,14)

InChIKey

MNJBMPQTXVZMFZ-UHFFFAOYSA-N

LogP

0.8012999999999995

Topological Polar Surface Area

45.39 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

201

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
2-Pyridinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-
5-[(4-ethyl-1-piperazinyl)methyl]-2-Pyridinamine
5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-amine
LY2835219 Intermediate 1
5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-ylamine
[5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl]amine
MNJBMPQTXVZMFZ-UHFFFAOYSA-N
BCP15949
2951AA
SY116161
A2438
J3.496.266I
5-((4-ethylpiperazin-

MDL Number

MFCD14706690

Customs Code

2933990090

FAQ

What is Abemaciclib Impurity 16 (CAS: 1180132-17-5)?

Abemaciclib Impurity 16 (CAS: 1180132-17-5) is a minor impurity of the drug abemaciclib, used in the treatment of certain types of breast cancer. It is a chemical compound with a specific structure but is not used therapeutically.

What are the main uses of Abemaciclib Impurity 16 (CAS: 1180132-17-5)?

Abemaciclib Impurity 16 (CAS: 1180132-17-5) is primarily used in the pharmaceutical industry for quality control and to ensure the purity of the drug abemaciclib. It is not used for any other significant applications.

Is Abemaciclib Impurity 16 (CAS: 1180132-17-5) safe?

Abemaciclib Impurity 16 (CAS: 1180132-17-5) is considered safe when handled properly. It is important to follow all safety guidelines and use appropriate personal protective equipment when working with this compound.

How should Abemaciclib Impurity 16 (CAS: 1180132-17-5) be stored?

Abemaciclib Impurity 16 (CAS: 1180132-17-5) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation and contamination. Optimal storage conditions include a temperature range of 2°C to 8°C (36°F to 46°F).