2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione

Basic Information

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CAS Number

118-29-6

Molecular Formula

C9H7NO3

Molecular Weight

177.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

144.0 to 148.0 deg-C

Boiling Point

332°C at 760 mmHg

Flash Point

332 oC at 760 mmHg

Refractive Index

1.5200 (estimate)

SMILES

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C1=CC=C2C(=C1)C(=O)N(C2=O)CO

InChI

InChI=1S/C9H7NO3/c11-5-10-8(12)6-3-1-2-4-7(6)9(10)13/h1-4,11H,5H2

InChIKey

MNSGOOCAMMSKGI-UHFFFAOYSA-N

LogP

0.23240000000000016

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

227

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Tox21_200859
2-(hydroxymethyl)-2,3-dihydro-1H-isoindole-1,3-dione
F0777-0575
CHEMBL3183835
1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-
DTXCID506954
N-hydroxymethyl-phthalimide
InChI=1/C9H7NO3/c11-5-10-8(12)6-3-1-2-4-7(6)9(10)13/h1-4,11H,5H
N-(Hydroxymethyl)phthalimide
PHTHALIMIDE, N-(HYDROXYMETHYL)-
5-21-10-00366 (Beilstein Handbook Reference)
2-(hydroxymethyl)-isoindole-1,3-dione
NSC39723
2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione
H0648
Oxymethylphthalimide
AI3-28943
2-(hydroxymethyl)-1,3-isoindolinedione
PIMOH (N-Hydroxymethyl phthalimide acid
NSC 27350
EINECS 204-241-4
N-(hydroxymethyl)-phthalimide
2-(hydroxymethyl)isoindole-1,3-dione
N-hydroxy methylphthalimide
NSC-27350
N-Hydroxymethylphthalimide
BCP27127
AKOS000269457
CS-0015898
N--(hydroxymethyl)-phthalimide
N-(hydroxymethy) phthalimide

MDL Number

MFCD00005899

Customs Code

29251995

FAQ

What is 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6)?

2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) is a heterocyclic organic compound with the chemical formula C8H6O3. It features a hydroxymethyl group attached to an isoindole-1,3-dione ring, making it a key intermediate in pharmaceutical and chemical syntheses. The compound is known for its stability and reactivity in organic reactions, often used in the production of dyes, drugs, and materials science applications.

What are the main uses of 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6)?

2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) is primarily used in pharmaceuticals as a building block for synthesizing bioactive compounds. It also serves in industrial applications, such as dye production and polymer chemistry. In research, it acts as a versatile intermediate for creating functionalized materials and studying chemical reactivity. Its unique structure makes it valuable for drug development and organic synthesis processes.

Is 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) safe?

2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) is generally considered safe when handled properly. However, it may cause skin or eye irritation, so protective measures like gloves and safety goggles are recommended. Safety standards emphasize avoiding prolonged exposure and ensuring proper ventilation. Always follow OSHA guidelines for handling chemical compounds in industrial or laboratory settings.

How should 2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) be stored?

2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione (CAS: 118-29-6) should be stored in a cool, dry place, away from light and moisture. Keep it in a sealed, airtight container to maintain stability. Storage conditions typically require temperatures below 25°C and low humidity. Avoid exposure to incompatible substances and ensure proper labeling for safe handling and storage.