Dexamethasone acetate | CAS No. 1177-87-3

Dexamethasone acetate

Basic Information

CAS Number

1177-87-3

Molecular Formula

C24H31FO6

Molecular Weight

434.5 g/mol

EINECS

214-646-8

AD

Basic Physical Properties

Physical State

White

Melting Point

238-240 °C

Boiling Point

579.4±50.0 °C(Predicted)

Density

1.1517 (estimate)

Water Solubility

13mg/L(25 ºC)

Flash Point

304.2±30.1 °C

Solubility

Soluble at 100 mg/ml in acetone

Refractive Index

87 ° (C=1, Dioxane)

Specific Rotation

D25 +73° (chloroform) (Arth, 1958); D +77.6° (Oliveto)

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C)O)C)O)F)C

InChI

InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChIKey

AKUJBENLRBOFTD-RPRRAYFGSA-N

LogP

2.466500000000001

pKa

12.08±0.70(Predicted)

Topological Polar Surface Area

100.9 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

910

Safety Information

View Safety Information

GHS Hazard Pictograms

H317H317

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-, 21-acetate
  • CHEMBL1530428
  • CHEBI:4463
  • 9.alpha.-Fluoro-16.alpha.-methylprednisolone acetate
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-, 21-acetate
  • HMS2095I22
  • Pregna-1,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-, acetate
  • 21-O-Acetyl Dexamethasone
  • HMS1568I22
  • Tox21_110499
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-
  • EINECS 214-646-8
  • BDBM50103620
  • Decadronal
  • 9alpha-Fluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate
  • UNII-K7V8P532WP
  • BPBio1_000198
  • AKUJBENLRBOFTD-RPRRAYFGSA-N
  • dexamethasone acetate, (6alpha,11beta)-isomer
  • Pregna-1,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-, 21-acetate
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11b,16a)-
  • Fortecortin (crystal suspension)
  • NCGC00022662-06
  • SR-01000000099-2
  • EN300-19631802
  • Decaject-L.A. (TN)
  • Prednisolone, 9.alpha.-fluoro-16.alpha.-methyl-, acetate
  • dexamethason acetate
  • Dexamethasoni acetas monohydrate
  • 16.alpha.-Methyl-9.alpha.-fluoroprednisolone 21-acetate
  • 9-Fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione acetate

MDL Number

MFCD00027407

EC Number

214-646-8

Customs Code

29372290

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