(1R)-1-(3-Chlorophenyl)-1-propanamine

Basic Information

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CAS Number

1168139-52-3

Molecular Formula

C9H12ClN

Molecular Weight

169.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

235.0±15.0 °C at 760 mmHg

Density

1.1±0.1 g/cm3

Flash Point

108.9±8.4 °C

Vapor Pressure

0.1±0.5 mmHg at 25°C

SMILES

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CCC(C1=CC(=CC=C1)Cl)N

InChI

InChI=1S/C9H12ClN/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6,9H,2,11H2,1H3/t9-/m1/s1

InChIKey

PLIWCUPYMOIFAV-SECBINFHSA-N

LogP

2.7498000000000005

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

116

Synonyms & References

English

(1R)-1-(3-Chlorophenyl)propan-1-amine
(R)-1-(3-Chloro-phenyl)-propylamine, AldrichCPR
(R)-1-(3-Chloro-phenyl)-propylamine
AKOS012669872
AS-47277
(R)-1-(3-chloro phenyl)propan-1-amine
MFCD06761924
1168139-52-3
F13059
DTXSID10649742
(R)-1-(3-CHLOROPHENYL)PROPAN-1-AMINE
CS-0005311
AKOS015842045
SCHEMBL8037342
Benzenemethanamine, 3-chloro-.alpha.-ethyl-, (.alpha.R)-

MDL Number

MFCD06761924

FAQ

What are the physical and chemical properties of (1R)-1-(3-Chlorophenyl)-1-propanamine (CAS: 1168139-52-3)?

(1R)-1-(3-Chlorophenyl)-1-propanamine is a colorless or white crystalline solid with a molecular weight of approximately 182.6 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong oxidizing agents. It has a pKa of about 8.5 and a moderate basicity.

How is (1R)-1-(3-Chlorophenyl)-1-propanamine (CAS: 1168139-52-3) typically synthesized?

(1R)-1-(3-Chlorophenyl)-1-propanamine is typically synthesized via the reduction of 3-chloro-N-phenylethylamine using a suitable reducing agent like sodium borohydride. This process provides good yield and good selectivity, making it a reliable method for the production of this compound.

What industries use (1R)-1-(3-Chlorophenyl)-1-propanamine (CAS: 1168139-52-3)?

(1R)-1-(3-Chlorophenyl)-1-propanamine is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds and as a precursor in the development of new drugs. It has also found applications in the polymer industry for the formulation of certain polymers and in the semiconductor industry as a dopant material.

What precautions should be taken when handling (1R)-1-(3-Chlorophenyl)-1-propanamine (CAS: 1168139-52-3)?

When handling (1R)-1-(3-Chlorophenyl)-1-propanamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.