(3S)-pyrrolidin-3-amine;dihydrochloride

Basic Information

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CAS Number

116183-83-6

Molecular Formula

C4H12Cl2N2

Molecular Weight

159.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

325°C (dec.)

Density

0.9840

Water Solubility

very faint turbidity

Refractive Index

1.1 ° (C=10, H2O)

Specific Rotation

1.1° (C=10, H2O)

SMILES

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C1CNCC1N.Cl.Cl

InChI

InChI=1S/C4H10N2.2ClH/c5-4-1-2-6-3-4;;/h4,6H,1-3,5H2;2*1H/t4-;;/m0../s1

InChIKey

NJPNCMOUEXEGBL-FHNDMYTFSA-N

LogP

0.1505999999999999

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

44.8

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

(3S)-pyrrolidin-3-amine dihydrochloride
(3S)-3-aminopyrrolidine dihydrochloride
(S)-pyrrolidin-3-amine dihydrochloride
TS-02111
MFCD00070605
3-Pyrrolidinamine, dihydrochloride, (3S)-
(S)-(+)-3-Aminopyrrolidine dihydrochloride
AC-6713
(S)-(+)-3-AMINOPYRROLIDINE 2HCL
AS-79988
(3S)-(+)-3-Aminopyrrolidine Dihydrochloride
A1054
(R)-(-)-3-Aminopyrrolidine dihydrochloride
DTXSID20542331
(S)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE
(3S)-Pyrrolidin-3-amine--hydrogen chloride (1/2)
(3S)-pyrrolidin-3-amine;dihydrochloride
SCHEMBL4717529
NJPNCMOUEXEGBL-FHNDMYTFSA-N
EN300-2009560
116183-83-6
(S)-pyrrolidin-3-aminedihydrochloride
AM81993
AKOS015845483
(S)-3-Aminopyrrolidine 2HCl
(3S)-(+)-3-Aminopyrrolidine dihydrochloride
(S)-3-aminopyrrolidine dihydrochloride
(S)-3-Aminopyrroline dihydrochloride
3-Nitro-4,5-dihydroxybenzaldehyde
(3S)-pyrrolidin-3-amine,dihydrochloride
(S)-Pyrrolidin-3-amine dihydrochloride

MDL Number

MFCD00070605

Customs Code

2933990090

FAQ

What regulatory guidelines apply to (3S)-pyrrolidin-3-amine; dihydrochloride (CAS: 116183-83-6)?

Regulatory guidelines for (3S)-pyrrolidin-3-amine; dihydrochloride (CAS: 116183-83-6) include GHS classification for handling and storage. It is subject to REACH regulations in the EU, which require registration if manufactured or imported in quantities exceeding one tonne per year. In the USA, the FDA and EPA regulate its use and disposal, ensuring compliance with environmental and health standards.

Are there alternatives to (3S)-pyrrolidin-3-amine; dihydrochloride in synthesis?

Alternative reagents to (3S)-pyrrolidin-3-amine; dihydrochloride include other amines such as (2S)-pyrrolidin-2-amine and (3R)-pyrrolidin-3-amine. These can serve as viable substitutes depending on the specific chemical reaction and desired product purity. Isomers and analogs may also be used based on the research requirements and availability.

What is the market or research trend for (3S)-pyrrolidin-3-amine; dihydrochloride?

The market for (3S)-pyrrolidin-3-amine; dihydrochloride (CAS: 116183-83-6) is growing due to its applications in pharmaceuticals, agrochemicals, and cosmetic industries. Research trends focus on its use as a chiral building block in asymmetric synthesis, with increasing demand for enantiomerically pure compounds. Price trends indicate stable demand, with potential for higher costs due to supply chain complexities.

How should waste containing (3S)-pyrrolidin-3-amine; dihydrochloride be handled?

Waste containing (3S)-pyrrolidin-3-amine; dihydrochloride (CAS: 116183-83-6) should be collected in appropriate containers labeled with the chemical name and CAS number. Ensure all waste is neutralized before disposal to prevent environmental harm. Incineration is a common method for disposal, but professional waste disposal services are recommended. Always follow local regulations and environmental protection precautions to ensure safe and compliant handling.