N-[(Benzyloxy)carbonyl]phenylalanine

Basic Information

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CAS Number

1161-13-3

Molecular Formula

C17H17NO4

Molecular Weight

299.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

85.0 to 89.0 deg-C

Boiling Point

511.5°C at 760 mmHg

Flash Point

263.1℃

Refractive Index

5.3 ° (C=4, AcOH)

Specific Rotation

5 º (c=5,acetic acid)

SMILES

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C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C17H17NO4/c19-16(20)15(11-13-7-3-1-4-8-13)18-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,18,21)(H,19,20)/t15-/m0/s1

InChIKey

RRONHWAVOYADJL-HNNXBMFYSA-N

LogP

2.6087000000000007

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

360

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

n-benzyloxycarbonyl-l-phenyl alanine
N-alpha-Benzyloxycarbonyl-L-phenylalanine
CBZ-L-PHE
AS-12743
((benzyloxy)carbonyl)-L-phenylalanine
CS-W012139
N-(Carbobenzyloxy)-L-phenylalanine
Cbz-Phe-OH
Z-L-Phenylalanine
(S)-2-(Benzyloxycarbonylamino)-3-phenylpropanoicacid
N-[(Benzyloxy)carbonyl]phenylalanine #
nalpha-benzyloxycarbonyl-l-phenylalanine
EINECS 214-599-3
Z-Phe
Alanine, N-carboxy-3-phenyl-, N-benzyl ester, L-
N-Benzyloxycarbonyl-(L)-Phenylalanine
(2S)-2-{[(Benzyloxy)carbonyl]amino}-3-phenylpropanoic acid
CBZ-L-Phenylalanine
N-Benzyloxycarbonyl-L-3-phenylalanine
C0660
N-Carbobenzyloxy-L-phenylalanine
N-carbobenzoxy-phenylalanine
AKOS015839335
Nalpha -[(phenylmethoxy)carbonyl]-L-phenylalanine
L-Phenylalanine, N-((phenylmethoxy)carbonyl)-
J-300211
N-Cbz-phenylalanine
N-[(Benzyloxy)carbonyl]phenylalanine
BDBM50043796
ZPheOH
(S)-2-Benzyloxycarbonylamino-3-phenyl-propionic acid

MDL Number

MFCD00020418

Customs Code

2924299090

FAQ

What is N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3)?

N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) is an amino acid derivative with the chemical formula C15H15NO4. It features a benzyloxy carbonyl (Z) group protecting the amino side chain of phenylalanine. This compound is a white solid with limited solubility in water and is commonly used in organic synthesis as a building block for peptides and pharmaceuticals.

What are the main uses of N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3)?

N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) is primarily used in pharmaceutical research for peptide synthesis and drug development. It serves as a protecting group in the creation of bioactive molecules and is also employed in industrial chemical processes. Additionally, it plays a role in studying protein structures and enzyme mechanisms in research laboratories.

Is N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) safe?

N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) is generally considered safe when handled properly. However, it should be treated with standard chemical safety precautions, such as wearing gloves, goggles, and lab coats. Avoid inhalation or skin contact, and ensure adequate ventilation. Always follow OSHA and EPA guidelines for safe handling and disposal.

How should N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) be stored?

N-[(Benzyloxy)carbonyl]phenylalanine (CAS: 1161-13-3) should be stored in a cool, dry, and dark place, preferably at 2-8°C. Keep in airtight containers to prevent moisture exposure and maintain stability. Avoid exposure to light and heat sources. Ensure proper labeling and store in a designated chemical storage area to maintain safety and shelf life.