2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl | CAS No. 1160861-59-5

2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl

Basic Information

CAS Number

1160861-59-5

Molecular Formula

C43H61O2P

Molecular Weight

640.93 g/mol

AD

Basic Physical Properties

Melting Point

231-235 °C

Solubility

Insuluble (4.6E-7 g/L) (25 ºC),

CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C34CC5CC(C3)CC(C5)C4)C67CC8CC(C6)CC(C8)C7)OC)OC)C(C)C

InChI

InChI=1S/C43H61O2P/c1-25(2)34-17-35(26(3)4)39(36(18-34)27(5)6)40-37(44-7)9-10-38(45-8)41(40)46(42-19-28-11-29(20-42)13-30(12-28)21-42)43-22-31-14-32(23-43)16-33(15-31)24-43/h9-10,17-18,25-33H,11-16,19-24H2,1-8H3

InChIKey

NMGHOZQCYNKWBG-UHFFFAOYSA-N

LogP

11.785799999999986

Topological Polar Surface Area

18.46 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

934

Synonyms & References

English

  • Di(adamantan-1-yl)(2',4',6'-triisopropyl-3,6-dimethoxy-2-biphenyl yl)phosphine
  • AdBrettPhos
  • 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl
  • Di-Ad-BrettPhos
  • AC1L3VYX
  • Ambap
  • decahydro-3,5,1,7-(1,2,3,4)butanetetraylnaphthalene
  • decahydro-3,5,1,7-[1,2,3,4]butanetetraylnaphthalene
  • Diadamantane
  • di-adamantyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine
  • Diamantane
  • DIAMANTINE
  • pentacyclo[7.3.1.1(4,12).0(2,7).0(6,11)]tetradecane
  • 1160861-59-5
  • SY070329
  • SCHEMBL18191395
  • BIS(ADAMANTAN-1-YL)({2',4',6'-TRIISOPROPYL-3,6-DIMETHOXY-[1,1'-BIPHENYL]-2-YL})PHOSPHANE
  • MFCD23379935
  • A893630
  • Y-200024
  • F10194
  • Di(adamantan-1-yl)(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine
  • 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl, Min. 95% AdBrettPhos
  • Phosphine, [3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]bis(tricyclo[3.3.1.13,7]dec-1-yl)-
  • AdBrettPhos, 95%
  • Di(1-adamantyl)(2 inverted exclamation mark ,4 inverted exclamation mark ,6 inverted exclamation mark -triisopropyl-3,6-dimethoxy-2-biphenylyl)phosphine
  • bis(1-adamantyl)-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane

MDL Number

MFCD23379935

FAQ

What regulatory guidelines apply to 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl (CAS: 1160861-59-5)?

This compound falls under the scope of the REACH regulations in Europe. In the United States, FDA and EPA have relevant regulations for chemical safety and environmental protection. It is also subject to GHS classification, which categorizes it based on its health, physical, and environmental hazards. Proper storage and handling procedures should comply with these guidelines to ensure safety and regulatory compliance.

Are there alternatives to 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl (CAS: 1160861-59-5) in synthesis?

There are alternative reagents and substituents that can be used in similar synthesis pathways. Common analogs include other phosphine ligands and biphenyl derivatives. However, the choice of alternative should consider the specific reaction conditions and the desired product properties to ensure comparable performance and efficiency.

What is the market or research trend for 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl (CAS: 1160861-59-5)?

This compound is primarily used in catalytic processes, particularly in palladium-catalyzed cross-coupling reactions. Market trends show increasing demand in pharmaceutical and fine chemical applications due to its unique reactivity. Research is also exploring its use in more complex catalytic systems, with a focus on improving selectivity and efficiency.

How should waste containing 2-(Di-1-adaMantylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl (CAS: 1160861-59-5) be handled?

Waste containing this compound should be collected in appropriate containers and stored under non-reactive conditions to prevent degradation. Disposal should be handled by professional waste management services to ensure compliance with environmental regulations. Incineration may be an option, but it must be conducted in a way that minimizes emissions and adheres to local and international environmental standards.

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