1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene

Basic Information

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CAS Number

116-29-0

Molecular Formula

C12H6Cl4O2S

Molecular Weight

356.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

146.5-147.5°

Boiling Point

484 °C at 760 mmHg

Flash Point

246.5 °C

Refractive Index

1.623

Vapor Pressure

0.0±1.2 mmHg at 25°C

SMILES

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O=S(C1=C(Cl)C=C(Cl)C(Cl)=C1)(C2=CC=C(Cl)C=C2)=O

InChI

InChI=1S/C12H6Cl4O2S/c13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-6H

InChIKey

MLGCXEBRWGEOQX-UHFFFAOYSA-N

LogP

5.133000000000002

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

400

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Toxicity

LD50 orally in rats: 556 mg/kg (Ben-dyke)

Synonyms & References

English

1,2,4-Trichloro-5-((4-chlorophenyl)sulfonyl)benzene
4-chlorophenyl 2,4,5-trichlorophenyl sulphone
P-CHLOROPHENYL-2,4,5-TRICHLOROPHENYL SULFONE
TEDION
TEDION V-18
TEDION V-18(R)
TEDONE
1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-benzen
1,2,4-trichloro-5-((4-chlorophenyl)-sulfonyl)benzene
Tetradifon
Tetradifon Solution
1,2,4-trichloro-5-(4-chlorobenzene-1-sulfonyl)benzene
1,2,4-trichloro-5-(4-chlorophenyl)sulfonylbenzene
1,2,4-trichloro-5-[(4-chlorophenyl)sulfonyl]benzene
4-chlorophenyl 2,4,5-trichlorophenyl sulfone
Tetradifon100µg
Sulfone,p-chlorophenyl 2,4,5-trichlorophenyl (7CI,8CI)
2,4,4',5-Tetrachlorodiphenylsulfone
Akaritox
Aredion
Duphar
Mition
Polacaritox
Roztoczol
Roztoczolextra
Tedion V 18
Tetradiphon
V 18
p-Chlorophenyl2,4,5-trichlorophenyl sulfone
V-18
TCDS

MDL Number

MFCD00018127

Customs Code

2930909054

FAQ

What are the physical and chemical properties of 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene (CAS: 116-29-0)?

1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene is a crystalline solid with a high molecular weight. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. Chemically, it exhibits moderate reactivity, particularly towards nucleophiles and bases. It is sparingly soluble in water with a molecular weight of approximately 371.04 g/mol.

How is 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene (CAS: 116-29-0) typically synthesized?

1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene is synthesized via a multi-step process involving the coupling of 4-chlorobenzenesulfonyl chloride with 1,2,4-trichlorobenzene. The reaction typically requires a Lewis acid catalyst and is carried out in an inert solvent. The overall yield is moderate, and the reaction is selective for the desired product.

What industries use 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene (CAS: 116-29-0)?

1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the production of special polymers, and in the semiconductor industry for its use in microelectronic applications. Additionally, it finds applications in the development of sensors and as a reagent in analytical chemistry.

What precautions should be taken when handling 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene (CAS: 116-29-0)?

When handling 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbents, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.