Diphenyl(4-piperidinyl)methanol

Basic Information

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CAS Number

115-46-8

Molecular Formula

C18H21NO

Molecular Weight

267.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

161.0 to 164.0 deg-C

Boiling Point

410.55°C (rough estimate)

Flash Point

142°C

Refractive Index

1.5100 (estimate)

SMILES

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C1CNCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O

InChI

InChI=1S/C18H21NO/c20-18(15-7-3-1-4-8-15,16-9-5-2-6-10-16)17-11-13-19-14-12-17/h1-10,17,19-20H,11-14H2

InChIKey

ZMISODWVFHHWNR-UHFFFAOYSA-N

LogP

2.9221000000000013

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

268

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

IDI1_012420
Prestwick1_000093
Calmeran
Azacyclonolum [INN-Latin]
Prestwick2_000093
BSPBio_000046
NCGC00016366-01
Azacyclonol (MDL 4829)
MDL 4829
Diphenyl(4-piperidinyl)methanol
Oprea1_848733
DTXSID2045280
Maybridge3_001033
a-(4-Piperidyl)benzhydrol
4-(Diphenylhydroxymethyl)piperidine
HMS2095C08
BDBM50017724
SR-01000640550
DTXCID0025280
Tox21_110399
Q4832014
Diphenyl(piperidin-4-yl)methanol (Azacyclonol)
Azaciclonolo
AM20020238
AS-13114
UNII-2MMR990PEM
AZACYCLONOL [WHO-DD]
MLS001201777
Diphenyl-piperidin-4-yl-methanol
4-Piperidinemethanol, .alpha.,.alpha.-diphenyl-

MDL Number

MFCD00066980

Customs Code

29333999

FAQ

What is Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8)?

Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) is an organic compound with the chemical formula C16H19NO. It features a methanol group attached to a piperidine ring, which is linked to two phenyl groups. This compound is known for its chiral structure and is commonly used in pharmaceutical and research applications. It is typically a white solid with moderate solubility in organic solvents and exhibits specific chemical reactivity due to its functional groups.

What are the main uses of Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8)?

Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) is primarily used as a synthetic intermediate in pharmaceutical research, particularly in the development of drugs targeting neurological disorders. It also serves as a chiral ligand in asymmetric catalysis and is employed in organic synthesis for creating complex molecules. Its applications extend to medicinal chemistry and industrial processes where stereochemistry is critical.

Is Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) safe?

Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation or ingestion should be avoided. Safety standards recommend using appropriate protective equipment, such as gloves and goggles, and working in a well-ventilated area. Always follow OSHA guidelines and consult safety data sheets for proper disposal and exposure limits.

How should Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) be stored?

Diphenyl(4-piperidinyl)methanol (CAS: 115-46-8) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. Keep it in a sealed container to prevent moisture and air exposure. Avoid contact with strong oxidizing agents and ensure it is stored away from heat sources. Proper storage conditions are essential to preserve its chemical integrity and ensure safety.