N-[(Benzyloxy)carbonyl]-L-valine

Basic Information

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CAS Number

1149-26-4

Molecular Formula

C13H17NO4

Molecular Weight

251.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

59.0 to 62.0 deg-C

Boiling Point

394.43°C (rough estimate)

Flash Point

215.4℃

Refractive Index

-4.3 ° (C=2, AcOH)

Specific Rotation

-4 º (c=2,acetic acid)

SMILES

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CC(C)C(C(=O)O)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C13H17NO4/c1-9(2)11(12(15)16)14-13(17)18-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3,(H,14,17)(H,15,16)/t11-/m0/s1

InChIKey

CANZBRDGRHNSGZ-NSHDSACASA-N

LogP

2.022

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

285

Safety Information

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GHS Hazard Pictograms

H315

H334

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

L-Valine, N-[(phenylmethoxy)carbonyl]-
(S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoic acid
HY-W008753
AC-24056
z-valine
NS00045935
Z-L-VAL-OH
AC-7044
AKOS015924215
L-VALINE, N-CBZ PROTECTED
CBZ-L-valine
carbobenzoxy-(S)-valine
N-(benzyioxycarbonyl)-L-valine
Benzyloxycarbonyl-L-valine
CCG-256518
2-(S)-[(benzyloxycarbonyl)amino]-3-methylbutyric acid
(s)-n-cbz-valine
N-CBZ-L -valine
P16425
AKOS010371619
N-alpha-BenZyloxycarbonyl-L-valine (CbZ-L-Val-OH)
MFCD00008922
Carbobenzyloxy-L-valine, 99%
M03071
(2S)-2-((BENZYLOXYCARBONYL)AMINO)-3-METHYLBUTANOIC ACID
SCHEMBL220569
N-Cbz-valine
N-CBZ-L-VALINE
N-(Benzyloxycarbonyl)-L-valine
CS-W009469
Z-L-Valine

MDL Number

MFCD00008922

Customs Code

2924299090

FAQ

What is N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4)?

N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) is a protected amino acid derivative commonly used in organic synthesis. It has the chemical formula C14H17NO4 and is known for its stability and utility in peptide chemistry. This compound contains a benzyloxycarbonyl (Z) group, which is often used as a protecting group for amino acids during chemical reactions.

What are the main uses of N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4)?

N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) is primarily used in pharmaceutical research and development, particularly in the synthesis of peptides and proteins. It also finds applications in the production of drug intermediates and as a building block in organic chemistry. Its use is relevant in biochemistry and medicinal chemistry due to its role in protecting the amino group during chemical modifications.

Is N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) safe?

N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) is generally considered safe when handled properly. It is a solid chemical compound with low reactivity under normal conditions. However, standard laboratory safety precautions should be followed, including wearing appropriate personal protective equipment (PPE) and ensuring proper ventilation. Safety data sheets (SDS) should be consulted for detailed handling guidelines.

How should N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) be stored?

N-[(Benzyloxy)carbonyl]-L-valine (CAS: 1149-26-4) should be stored in a cool, dry, and dark place to maintain its stability. It is typically kept in a sealed container at a temperature below 25°C and away from moisture and light. Proper storage helps preserve the integrity of the benzyloxycarbonyl (Z) protecting group, ensuring optimal performance in chemical applications.