Fondaparinux Sodium

Basic Information

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CAS Number

114870-03-0

Molecular Formula

C31H43N3Na10O49S8

Molecular Weight

1728.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

°Cat760mmHg

Specific Rotation

D23 +48° (c = 0.61 in water)

SMILES

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COC1C(C(C(C(O1)COS(=O)(=O)[O-])OC2C(C(C(C(O2)C(=O)[O-])OC3C(C(C(C(O3)COS(=O)(=O)[O-])OC4C(C(C(C(O4)C(=O)[O-])OC5C(C(C(C(O5)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O)NS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56;;;;;;;;;;/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68);;;;;;;;;;/q;10*+1/p-10/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-;;;;;;;;;;/m1........../s1

InChIKey

XEKSTYNIJLDDAZ-JASSWCPGSA-D

LogP

-9.34120

Complexity

3330

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Fondaparinux sodium [USAN]
FONDAPARINUX SODIUM [EMA EPAR]
Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-O-beta-D-glucopyra-nuronosyl-(1->4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1->4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, decasodium salt
FONDAPARINUX SODIUM [ORANGE BOOK]
alpha-D-Glucopyranoside, methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-4)-O-beta-D-glucopyranuronosyl(1-4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1-4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate), decasodium salt
fondaparinuxum natricum
FONDAPARINUX SODIUM [USP MONOGRAPH]
IC 85158
SR-90107A
B01AX05
D01844
FONDAPARINUX SODIUM [JAN]
CHEMBL1200644
Fondaparinux (sodium)
Q421218
Fondaparinux sodium (JAN/USP/INN)
alpha-D-Glucopyranoside, methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-->4)-O-beta-D-glucopyranuronosyl-(1-->4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-->4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1-->4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate), sodium salt (1:10)
GSK-576428
Fondaparinux sodium?
BDBM50604260
Methly O-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-4)-O-beta-D-glucopyranuronosyl-(1-4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1-4)-O-2-O-sulfo-alpha-L-idopyranuronosyl-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, decasodium salt
AS-80003
FONDAPARINUX SODIUM [MART.]
Natural heparin pentasaccharide Sodium
Decasodium methyl O-(2-deoxy-6-O-sulfo-2-sulfoamino-alpha-D-glucopyranosyl)-(1->4)-O-(beta-D-glucopyranosyluronic acid)-(1->4)-O-(2-deoxy-3,6-di-O-sulfo-2-sulfoamino-alpha-D-glucopyranosyl)-(1->4)-O-(2-O-sulfo-alpha-L-idopyranosyluronic acid)-(1->4)-2-deoxy-6-O-sulfo-2-sulfoamino-alpha-D-glucopyranoside
C71476
Fondaparin sodium
IC-851589
fondaparinux sodico
FONDAPARINUX SODIUM [INN]
DTXSID501027612

MDL Number

MFCD06794972

FAQ

What is Fondaparinux Sodium (CAS: 114870-03-0)?

Fondaparinux Sodium (CAS: 114870-03-0) is an anticoagulant drug that works by inhibiting factor Xa. It is a synthetic pentasaccharide derivative of heparin and has a chemical formula of C16H23Na3O13S2. It is commonly used in clinical settings for its anti-thrombotic properties and is known for its high specificity and potency compared to other anticoagulants.

What are the main uses of Fondaparinux Sodium (CAS: 114870-03-0)?

Fondaparinux Sodium (CAS: 114870-03-0) is primarily used in pharmaceuticals as an anticoagulant to prevent and treat blood clots. It is prescribed for conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and for patients undergoing surgery who are at risk of thromboembolic events. It is also utilized in research for studying coagulation mechanisms and developing new anticoagulant therapies.

Is Fondaparinux Sodium (CAS: 114870-03-0) safe?

Fondaparinux Sodium (CAS: 114870-03-0) is generally considered safe when used as directed, but it can cause side effects such as bleeding, allergic reactions, or thrombocytopenia. Proper handling and administration are essential to minimize risks. It is regulated by safety standards and should be used under medical supervision to ensure patient safety and efficacy.

How should Fondaparinux Sodium (CAS: 114870-03-0) be stored?

Fondaparinux Sodium (CAS: 114870-03-0) should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 2°C to 8°C (36°F to 46°F) and should be protected from moisture. Storage in airtight containers is recommended to maintain its stability and potency over time.