Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II) | CAS No. 1148148-01-9

Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II)

Basic Information

CAS Number

1148148-01-9

Molecular Formula

C43H62ClNO2PPd

Molecular Weight

797.8 g/mol

AD

Basic Physical Properties

Melting Point

198-204 °C

CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C3CCCCC3)C4CCCCC4)OC)OC)C(C)C.C1=CC=C([C-]=C1)CCN.Cl[Pd+]

InChI

InChI=1S/C35H53O2P.C8H10N.ClH.Pd/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28;9-7-6-8-4-2-1-3-5-8;;/h19-25,27-28H,9-18H2,1-8H3;1-4H,6-7,9H2;1H;/q;-1;;+2/p-1

InChIKey

IWMMXPNBCHCFCY-UHFFFAOYSA-M

Complexity

816

Synonyms & References

English

  • Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine-(2-(2-aminoethyl)phenyl)palladium(II) chloride
  • Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)
  • Brettphos Palladium(II)Phenethylamine Chloride
  • CHLORO[2-(DICYCLOHEXYLPHOSPHINO)-3,6-DIMETHOXY-2',4', 6'-TRIISOPROPYL-1,1'-BIPHENYL][2-(2-AMINOETHYL)PHENYL]PALLADIUM(I...
  • CHLORO[2-(DICYCLOHEXYLPHOSPHINO)-3,6-DIMETHOXY-2',4', 6'-TRIISOPROPYL-1,1'-BIPHENYL][2-(2-AMINOETHYL)PHENYL]PALLADIUM(II)
  • Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2\',4\',6\'-triisopropyl-1,1\'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)
  • 2,2,2-trichloroethyl pyruvate
  • AGN-PC-00KA75
  • Brenztraubensaeuretrichloraethylester
  • BrettPhos palladacycle
  • BrettPhos precatalyst
  • CTK2C9594
  • Propanoic acid, 2-oxo-, 2,2,2-trichloroethyl ester
  • Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II)
  • A894118
  • 1148148-01-9
  • Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)
  • AKOS028109735
  • Cl-[2-(dicyclohexylphosphino)-3,6-diMeO-2',4',6'-tri-i-prop-1,1'-biPh][2-(2-aminoethyl)Ph]Pd(II)
  • Chloro[2-(dicyclohexylphosphino)-2 inverted exclamation mark ,4 inverted exclamation mark ,6 inverted exclamation mark -triisopropyl-3,6-dimethoxybiphenyl][2-(2-aminoethyl)phenyl]palladium(II)
  • chloropalladium(1+);dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;2-phenylethanamine
  • Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-minoethyl)
  • BP-21209
  • Brett Phos pre Pd catalyst
  • O11708
  • Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]Pd(II)
  • SY027910
  • BrettPhos Palladacycle
  • C43H63ClNO2PPd
  • MFCD12545956

MDL Number

MFCD12545956

FAQ

What are the physical and chemical properties of Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II) (CAS: 1148148-01-9)?

The compound is a solid with a crystalline form. It has a high molecular weight due to its complex structure. It is poorly soluble in water but soluble in common organic solvents like ethanol and dichloromethane. Chemically, it is reactive and can undergo various transformations under certain conditions. It is a key ligand in palladium catalysis for cross-coupling reactions.

How is Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II) (CAS: 1148148-01-9) typically synthesized?

This compound is synthesized by a multi-step process involving the preparation of the Phosphine ligand, followed by its complexation with palladium(II). Common methods include the use of palladium(II) acetate and various phosphine ligands. The reaction typically has good selectivity and yield under appropriate conditions, making it suitable for use as a catalyst in cross-coupling reactions.

What industries use Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II) (CAS: 1148148-01-9)?

This compound is primarily used in the pharmaceutical and chemical industries, particularly in the synthesis of complex organic molecules. It is also used in the development of new catalysts for cross-coupling reactions, which are vital in the production of polymers and advanced materials. Its applications extend to the production of sensors and semiconductors where precise chemical transformations are required.

What precautions should be taken when handling Chloro(2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2-aminoethyl)phenyl)palladium(II) (CAS: 1148148-01-9)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that working is done in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and follow all laboratory safety protocols.

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