Apaziquone | CAS No. 114560-48-4

Apaziquone

Basic Information

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CAS Number

114560-48-4

Molecular Formula

C15H16N2O4

Molecular Weight

288.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CN1C(=C(C2=C1C(=O)C=C(C2=O)N3CC3)CO)C=CCO

InChI

InChI=1S/C15H16N2O4/c1-16-10(3-2-6-18)9(8-19)13-14(16)12(20)7-11(15(13)21)17-4-5-17/h2-3,7,18-19H,4-6,8H2,1H3

InChIKey

MXPOCMVWFLDDLZ-UHFFFAOYSA-N

LogP

0.10140000000000005

Topological Polar Surface Area

82.54 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

524

Synonyms & References

English

E 09
SCHEMBL367964
114560-48-4
EO9
Apaziquone
CS-0006128
1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-[(1E)-3-hydroxy-1-propen-1-yl]-1-methyl-
Apaziquonum
ANTINEOPLASTIC-382459
DB12593
5-(Azridin-1-yl)-3-(hydroxymethyl)-2-((1E)-3-hydroxyprop-1-enyl)-methyl-1H-indole-4,7-dione
1H-Indole-4, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-
(E)-5-(1-Azirinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-dione
CHEBI:177558
EOquin
NSC-382459
Neoquin
Apaziquone [USAN:INN]
1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-((1E)-3-hydroxy-1-propenyl)-1-methyl-
DTXSID90869587
D02965
NS00068596
H464ZO600O
E-85/050
APAZIQUONE [INN]
5-(1-Aziridinyl)-3-(hydroxymethyl)-2-[(1E)-3-hydroxy-1-propen-1-yl]-1-methyl-1H-indole-4,7-dione
NSC 382459
N1,N6-Diethyl-3-methylhexanediamide
Apaziquonum [INN-Latin]
Apaziquone [USAN]
SCHEMBL367965

MDL Number

MFCD00876411

FAQ

What is Apaziquone (CAS: 114560-48-4)?

Apaziquone (CAS: 114560-48-4) is a synthetic antitumor antibiotic with a unique chemical structure. It has a molecular formula of C21H22NO6 and exhibits significant antitumor activity, particularly against several types of cancer cells.

What are the main uses of Apaziquone (CAS: 114560-48-4)?

Apaziquone (CAS: 114560-48-4) is primarily used in preclinical and clinical research for studying antitumor properties. It is also explored for potential therapeutic applications in cancer treatment, though it has not yet been approved for clinical use.

Is Apaziquone (CAS: 114560-48-4) safe?

Apaziquone (CAS: 114560-48-4) is generally safe when used under proper laboratory conditions, but it can be toxic to cells and tissues. Users should follow safety guidelines, including wearing personal protective equipment and handling in a well-ventilated area or a fume hood.

How should Apaziquone (CAS: 114560-48-4) be stored?

Apaziquone (CAS: 114560-48-4) should be stored at a controlled room temperature (15-25°C), away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation and ensure its stability.