N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine

Basic Information

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CAS Number

114360-54-2

Molecular Formula

C21H23NO4

Molecular Weight

353.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

153.0 to 157.0 deg-C

Boiling Point

559.8°C at 760 mmHg

Density

1.2070

Water Solubility

Insoluble in water.

Flash Point

292.4±25.4 °C

Refractive Index

25 ° (C=1, DMF)

SMILES

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CC(C)CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1

InChIKey

CBPJQFCAFFNICX-LJQANCHMSA-N

LogP

4.024400000000003

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

484

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
AKOS015924103
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-LEUCINE
BDBM50121968
NCGC00024724-01
N- (9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
(2R)-2-(9H-luoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Fmoc-DLeu
KBioGR_000649
Fmoc-D-leucine
IDI1_001012
PD001396
Spectrum5_001340
J-300158
A803174
Z1123720095
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid
(r)-n-fmoc-leucine
Spectrum4_000165
(2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]-amino}-4-methylpentanoic acid
KBio3_002289
(NPC-15199)
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine
KBio2_007098
NCGC00024724-02
SPECTRUM1502083
Spectrum_001482
HMS503K05
NINDS_001012
NCGC00024724-03
HMS3675O14

MDL Number

MFCD00062957

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine (CAS: 114360-54-2)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine is a protected form of D-leucine used in organic synthesis and medicinal chemistry. It has the chemical formula C27H27NO4. This compound is highly reactive and serves as a valuable building block for synthesizing larger molecules.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine (CAS: 114360-54-2)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine is primarily used as a protecting group in organic synthesis, particularly in peptide and drug synthesis. It is also utilized in academic and industrial research for developing new pharmaceutical compounds and materials.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine (CAS: 114360-54-2) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine is generally considered safe for laboratory use when proper precautions are taken. However, it should be handled with care due to its reactivity. Protective gloves, goggles, and a lab coat are essential. It is non-toxic but avoid ingestion and contact with eyes and skin. Store in a cool, dry place away from direct sunlight and heat sources.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine (CAS: 114360-54-2) be stored?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine should be stored in a sealed container at a temperature below 25°C and away from direct sunlight. Maintain a relative humidity below 50%. Store in a cool, dry place, protected from light and air to prevent degradation. Ensure good ventilation in the storage area to avoid the accumulation of flammable gases.