N-[(Benzyloxy)carbonyl]-L-alanine

Basic Information

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CAS Number

1142-20-7

Molecular Formula

C11H13NO4

Molecular Weight

223.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

84.0 to 87.0 deg-C

Boiling Point

422.1°C at 760 mmHg

Flash Point

209.1℃

Refractive Index

-14.5 ° (C=2, AcOH)

Specific Rotation

-15 º (c=2, AcOH 24 ºC)

SMILES

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CC(C(=O)O)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1

InChIKey

TYRGLVWXHJRKMT-QMMMGPOBSA-N

LogP

1.3859000000000001

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

248

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

CBZ-L-ALA-OH
N-ALPHA-BENZYLOXYCARBONYL-L-ALANINE
NSC-88469
Alanine, N-carboxy-, N-benzyl ester, L-
N-benzyloxycarbonyl alanine
BDBM223538
N-Benzoxycarbonyl-L-alanine
N-carbobenzoxy-l-ala
N-Benzyloxycarbonylalanine, (L)-
HY-Y0007
(S)-2-benzyloxycarbonylaminopropionic acid
Q27095370
Alanine, N-[(phenylmethoxy)carbonyl]-
Cbz-D-Ala-OH
Z-Ala-OH
(S)-2-(BENZYLOXYCARBONYLAMINO)PROPANOIC ACID
J-300019
A803157
Carbobenzoxy-L-alanine
N-Benzyloxycarbonyl-L-alanine
AKOS005175180
L-Alanine, N-[(phenylmethoxy)carbonyl]-
(S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid
N-BENZYLOXYCARBONYL-L-SERINE-BETALACTONE
NSC 88469
L-Alanine, N-carboxy-, N-benzyl ester
NSC-156978
(S)-N-Cbz-alanine
EN300-82612
US9321743, Cbz-L-Ala
carbobenzoxy-alanine

MDL Number

MFCD00002640

Customs Code

2924299090

FAQ

What is N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7)?

N-[(Benzyloxy)carbonyl]-L-alanine, also known as Boc-L-alanine, is an amino acid derivative with the CAS number 1142-20-7. It features a benzyloxy carbonyl (Boc) protecting group attached to the alpha-amino group of L-alanine. This compound is commonly used in organic synthesis and pharmaceutical research due to its stability and utility in protecting amino functionalities.

What are the main uses of N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7)?

N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7) is primarily used in pharmaceuticals for synthesizing peptides and drugs, as a protecting group in L-alanine derivatives, and in research for organic chemistry applications. It also finds use in the production of chiral compounds and as a building block in biochemistry studies.

Is N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7) safe?

N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7) is generally considered safe when handled properly. It has low toxicity but should be treated with standard chemical safety precautions, such as wearing gloves and avoiding inhalation. Always follow guidelines from regulatory bodies like OSHA for safe handling and storage of organic compounds.

How should N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7) be stored?

N-[(Benzyloxy)carbonyl]-L-alanine (CAS: 1142-20-7) should be stored in a cool, dry place, away from light and moisture. Keep in a sealed, airtight container to maintain stability. For long-term storage, refrigeration is recommended to prevent degradation, ensuring optimal performance in chemical reactions and applications.