(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone | CAS No. 1141397-80-9

(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone

Basic Information

CAS Number

1141397-80-9

Molecular Formula

C9H14F2N2O5

Molecular Weight

268.22 g/mol

AD

Basic Physical Properties

Physical State

Solid powder

OC[C@H]1O[C@@H](N2CC[C@@H](O)NC2=O)C(F)(F)[C@@H]1O

InChI

1S/C9H14F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4-7,14-16H,1-3H2,(H,12,17)/t4-,5-,6-,7-/m1/s1

InChIKey

VUDZSIYXZUYWSC-DBRKOABJSA-N

LogP

-1.5665000000000002

Topological Polar Surface Area

102.26 Ų

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

343

Synonyms & References

English

  • Cedazuridine
  • 39IS23Q1EW
  • Cedazuridine [INN]
  • Cedazuridine [USAN]
  • Cedazuridine [USAN:INN]
  • BDBM50007029
  • WHO 10741
  • E7727
  • (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine
  • Uridine, 2'-deoxy-2',2'-difluoro-3,4,5,6-tetrahydro-, (4R)-
  • (4R)-4-Hydroxy-1-(2,2-difluoro-2-deoxy-beta-D-ribofuranosyl)-3,4,5,6-tetrahydropyrimidine-2(1H)-one
  • (4R)-1-(2-Deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone

MDL Number

MFCD32062663

FAQ

What is (4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone (CAS: 1141397-80-9)?

(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone is a chemical compound with a CAS number of 1141397-80-9. This compound is a synthetic intermediate primarily used in the development of antiviral drugs, particularly those targeting influenza and HIV. It exhibits antiviral activity through its interaction with viral enzymes, thus inhibiting viral replication.

What are the main uses of (4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone (CAS: 1141397-80-9)?

(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone is mainly used as a synthetic intermediate in the pharmaceutical industry, particularly in the development of antiviral drugs. Its primary applications include the production of antiviral compounds that target influenza and HIV by inhibiting viral enzymes, thereby preventing viral replication.

Is (4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone (CAS: 1141397-80-9) safe?

(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone is generally considered safe for use in the pharmaceutical industry, but safety precautions must be followed. It should be handled in a well-ventilated area and appropriate personal protective equipment should be worn. It is important to follow all safety guidelines and regulations to ensure the safe handling and storage of this compound.

How should (4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone (CAS: 1141397-80-9) be stored?

(4R)-1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)-4-hydroxytetrahydro-2(1H)-pyrimidinone should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and light from affecting the compound. Proper storage conditions are crucial to maintaining the stability and effectiveness of the compound during storage and transport.

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