Erythromycin | CAS No. 114-07-8

Erythromycin

Basic Information

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CAS Number

114-07-8

Molecular Formula

C37H67NO13

Molecular Weight

733.94 g/mol

Basic Physical Properties

Melting Point

138-140 ºC

Boiling Point

818.4°C at 760 mmHg

Water Solubility

Soluble in water at 2mg/ml

Solubility

ethanol: soluble

Refractive Index

-74 ° (C=2, EtOH)

Specific Rotation

-74.5 º (c=2, ethanol)

SMILES

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CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

InChI

InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChIKey

ULGZDMOVFRHVEP-RWJQBGPGSA-N

LogP

1.785600000000004

pKa

8.8(at 25℃)

Topological Polar Surface Area

193.91 Å²

Hydrogen Bond Donor/Acceptor

5 / 14

Complexity

1180

Safety Information

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GHS Hazard Pictograms

H303

Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

Hazard Class

Class 3 Class 3

Synonyms & References

English

Erythromycin
Abomacetin
Ak-Mycin
Aknin
Drmysin
E-Base
E.E.S
Emgel
EMU
E-mycin
Ergel
Eritocina
Eritrocina
Erthrogran
Eryacne
ERYC
Erycen
Erycette
Erycin
Erycinum
Ery Derm
Erymax
Erypar
ERY-PED
ERY-TAB
Erythro
Erythrocin
Erythroguent
Erythromast
Erythromast 36
Erythromid

MDL Number

MFCD00084654

Customs Code

2941500000

FAQ

What is Erythromycin (CAS: 114-07-8)?

Erythromycin (CAS: 114-07-8) is a macrolide antibiotic derived from *Streptomyces* species. It has the chemical formula C37H67NO13 and appears as a white to yellowish powder. Known for its broad-spectrum activity, it inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, making it effective against Gram-positive and some Gram-negative bacteria.

What are the main uses of Erythromycin (CAS: 114-07-8)?

Erythromycin (CAS: 114-07-8) is primarily used as an antibiotic to treat respiratory infections, skin infections, and other bacterial illnesses. It is also employed in veterinary medicine and as a research compound for antimicrobial studies. Its application extends to topical treatments and is recognized for its efficacy against antibiotic-resistant strains.

Is Erythromycin (CAS: 114-07-8) safe?

Erythromycin (CAS: 114-07-8) is generally safe when used as directed, but it may cause side effects like gastrointestinal discomfort, nausea, or allergic reactions. It is approved by the FDA and WHO for medicinal use. Proper handling, such as wearing gloves and avoiding contamination, is essential to ensure safety during storage and application.

How should Erythromycin (CAS: 114-07-8) be stored?

Erythromycin (CAS: 114-07-8) should be stored in a cool, dry place (15-25°C) away from light and moisture. Keep in airtight containers to maintain stability and prevent degradation. Avoid exposure to heat and light to preserve its potency and ensure long-term storage safety.