Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate | CAS No. 1138444-37-7

Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate

Basic Information

CAS Number

1138444-37-7

Molecular Formula

C12H11BrN2O2S

Molecular Weight

327.2 g/mol

AD

Basic Physical Properties

Melting Point

130-135 °C

CCOC(=O)c1c(nc(s1)c2ccccn2)CBr

InChI

InChI=1S/C12H11BrN2O2S/c1-2-17-12(16)10-9(7-13)15-11(18-10)8-5-3-4-6-14-8/h3-6H,2,7H2,1H3

InChIKey

RNJKUHUGSBTCRJ-UHFFFAOYSA-N

LogP

3.2767000000000017

Topological Polar Surface Area

52.08 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • Ethyl 4-bromomethyl-2-(2-pyridyl)thiazole-5-carboxylate
  • Ethyl 2-(2-pyridyl)-4-(bromomethyl)-thiazole-5-carboxylate
  • ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate
  • ACMC-20akwe
  • AG-L-44281
  • CTK6F8027
  • Ethyl-2(2-Pyridyl)-4-(bromomethyl)-thiazole-5-Carboxylate
  • Ethyl-4-(broMoMethyl)-2-(2-pyridyl)thiazole-5-carboxylate
  • KB-253296

MDL Number

MFCD11869291

FAQ

What is Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7)?

Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) is a thiazole derivative with a bromomethyl group and a pyridyl group attached to the thiazole ring. It is commonly used in medicinal chemistry and pharmaceutical research as an intermediate or a potential drug candidate.

What are the main uses of Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7)?

The main uses of Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) include its role as an intermediate in the synthesis of pharmaceuticals, particularly in the development of anti-inflammatory and antiviral drugs. It is also used in research for its potential biological activities.

Is Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) safe?

Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) is generally considered safe for laboratory use under proper handling conditions. However, it should be handled with caution due to its chemical nature. Protective gloves and goggles are recommended, and it should be stored in a fume hood. Avoid inhalation and skin contact.

How should Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) be stored?

Ethyl 4-(bromomethyl)-2-(2-pyridinyl)-1,3-thiazole-5-carboxylate (CAS: 1138444-37-7) should be stored in a cool, dry place away from direct sunlight and sources of heat. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should not exceed 25°C (77°F) to ensure its stability and safety.

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