(E)-N-[(Benzyloxy)(hydroxy)methylene]glycine

Basic Information

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CAS Number

1138-80-3

Molecular Formula

C10H11NO4

Molecular Weight

209.2 g/mol

Basic Physical Properties

Melting Point

118-122 °C

Boiling Point

424℃ at 760 mmHg

Water Solubility

Soluble in methanol. Insoluble in water.

Flash Point

210.2℃

Solubility

methanol: 0.1 g/mL, clear

Refractive Index

1.5400 (estimate)

SMILES

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C1=CC=C(C=C1)COC(=O)NCC(=O)O

InChI

InChI=1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)

InChIKey

CJUMAFVKTCBCJK-UHFFFAOYSA-N

LogP

0.9973999999999997

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

224

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Benzyloxycarbonylamino-Acetic Acid
((benzyloxy)carbonyl)glycine
Z-GlyOH
BRN 0526877
N-ALPHA-CBZ-GLYCINE
carbobenzoxy-glycine
N-[(benzyloxy)carbonyl]glycine
2-(((benzyloxy)carbonyl)amino)aceticacid
2-(((benzyloxy)carbonyl)amino)acetic acid
([(Benzyloxy)carbonyl]amino)acetic acid #
AB00257
Cbz-Glycine
N-Z-Gly-OH
Benzyloxycarbonylglycine
MFCD00002691
[(benzyloxy)-carbonyl]aminoacetic acid
Q-101746
N-Carbobenzyloxyglycine
Glycine, N-benzyl ester
2P-917
N-(carbobenzoxy)-glycine
CBZ-GLY
Oprea1_763666
carbobenzoxy-glycin
Z285919546
N-benzyloxycarbonyl glycine
N-(benzyloxycarbonyl) glycine
NSC-2526
N-(benzyloxycarbonyl)glycine
A803102
Benzyloxycarbonylamino-acetic acid anion

MDL Number

MFCD00002691

Customs Code

2924299090

FAQ

What is (E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3)?

(E)-N-[(Benzyloxy)(hydroxy)methylene]glycine, with CAS number 1138-80-3, is an organic compound that features a glycine backbone with a benzyloxy and hydroxy group connected via a methylene bridge. It exhibits a specific stereochemistry (E configuration) and is known for its structural versatility in synthetic chemistry. This compound is often used as an intermediate in the synthesis of various pharmaceutical and chemical products.

What are the main uses of (E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3)?

(E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3) is primarily used in pharmaceutical research for the development of drugs, particularly in the synthesis of chiral compounds and bioactive molecules. It also finds applications in organic synthesis, polymer chemistry, and as a precursor for various derivatives. Its utility extends to chemical research and industrial processes requiring controlled stereochemistry.

Is (E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3) safe?

(E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3) is generally considered safe when handled properly. However, as with many organic compounds, it should be treated with care to avoid skin contact and inhalation. Safety data sheets (SDS) recommend using protective gloves, goggles, and ventilation. It is important to follow established safety protocols to ensure safe usage in laboratory and industrial settings.

How should (E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3) be stored?

(E)-N-[(Benzyloxy)(hydroxy)methylene]glycine (CAS: 1138-80-3) should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container away from moisture and air. Storage at temperatures below 25°C is recommended, and it should be protected from light to prevent degradation. Always store in a well-ventilated area to ensure safety.