2-Bromo-3-isopropoxypyridine(CAS: 113503-65-4)

2-Bromo-3-isopropoxypyridine is a white crystalline solid with a molecular weight of 260.24 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. The compound is moderately reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored away from strong oxidizers and reducing agents.

2-Bromo-3-isopropoxypyridine is typically synthesized by the bromination of 3-isopropoxypyridine using N-bromosuccinimide (NBS) in an organic solvent like toluene. The reaction is carried out at room temperature with good yield and selectivity. Alternatively, it can be prepared by reacting 3-isopropoxypyridine with bromine in the presence of a cupric ion catalyst.

2-Bromo-3-isopropoxypyridine is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the preparation of materials for sensors and semiconductors due to its unique electronic properties. Additionally, it may have applications in the polymer industry for the development of new materials with specific properties.

When handling 2-Bromo-3-isopropoxypyridine, safety glasses and gloves should be worn. It should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be carefully cleaned up and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and storage instructions.