Baclofen | CAS No. 1134-47-0

Baclofen

Basic Information

CAS Number

1134-47-0

Molecular Formula

C10H12ClNO2

Molecular Weight

213.66 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

208°C

Boiling Point

364.3±32.0 °C at 760 mmHg

Water Solubility

Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6

Flash Point

174.1±25.1 °C

Solubility

1 M HCl: 50 mg/mL

Refractive Index

1.5500 (estimate)

Vapor Pressure

0.0±0.9 mmHg at 25°C

C1=CC(=CC=C1C(CC(=O)O)CN)Cl

InChI

InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)

InChIKey

KPYSYYIEGFHWSV-UHFFFAOYSA-N

LogP

1.857

Topological Polar Surface Area

63.32000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

191

Safety Information

View Safety Information

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H317 May cause an allergic skin reaction
Sensitization, Skin
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Hazard Class

Class 6.1 Class 6.1

Toxicity

LD50 in male mice, rats (mg/kg): 45, 78 i.v.; 103, 115 s.c.; 200, 145 orally (Tadokoro)

Synonyms & References

English

  • CCRIS 3722
  • HYDROCINNAMIC ACID, beta-(AMINOMETHYL)-p-CHLORO-
  • (+/- )-beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
  • Ba-34647
  • beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
  • HMS2091M03
  • NCGC00015156-04
  • BRN 2104494
  • NCGC00015156-13
  • NCGC00015156-11
  • OZOBAX
  • FT-0622547
  • .gamma.-Amino-.beta.-(p-chlorophenyl)butyric acid
  • Baclofenum (INN-Latin)
  • FT-0662469
  • SR-01000000107-8
  • Prestwick2_000085
  • NCGC00015156-28
  • BACLOFEN [USP-RS]
  • .beta.-(4-Chlorophenyl)gaba
  • SMR000058294
  • Gablofen
  • AB00051921
  • B3343
  • (+-)-Baclofen
  • Baclofen (R,S)
  • BACLOFEN [JAN]
  • Lioresal
  • HMS2095A12
  • LYVISPAH
  • Baclofen [USAN:USP:INN:BAN:JAN]

MDL Number

MFCD00055143

Customs Code

2922499990

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