3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine

Basic Information

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CAS Number

113-92-8

Molecular Formula

C16H19ClN2

Molecular Weight

390.87 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

132.0 to 136.0 deg-C

Boiling Point

379 oC at 760 mmHg

Water Solubility

1-5 g/100 mL at 21 ºC

Solubility

Solubility: Soluble in water

Refractive Index

1.6800 (estimate)

Vapor Pressure

2.9E-14mmHg at 25°C

SMILES

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CN(C)CCC(C1=CC=C(Cl)C=C1)C2=CC=CC=N2.O=C(O)/C=C\C(O)=O

InChI

InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3

InChIKey

SOYKEARSMXGVTM-UHFFFAOYSA-N

LogP

3.530400000000001

Topological Polar Surface Area

90.73000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

379

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1(b) Class 6.1(b)

Sensitiveness

sensitive to light

Toxicity

LD50 orally in mice: 162 mg/kg (Smith)

Synonyms & References

English

chlorphenamine hydrogen maleate
1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethy-laminopropanebimaleate
1-(p-chlorphenyl)-1-(2-pyridyl)-3-dimethylaminopropanmaleat
2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-pyridinmaleate(1:1)
allerclor
allergin
alunex
antagonate
carbinoxamidemaleate
Chlorphenamine maleate
Chlorpheniramine Maleate
Chlorpheniramine Maleate Salt
Chlorpheniramine maleate salt solution
Chloropheniramine maleate
(+/-)-CHLORPHENIRAMINE MALEATE SALT
(+/-)-CHLORPHENIRAMINE-D6 MALEATE
BISACODYL
CHLOROPHENAMINEMALEATE
CHLORPHENAMINE MALEATES
Chlorpheniramine (maleate)
CHLORPHENIRAMINE HYDROGEN MALEATE
ChlorpheniraMine Maleate Extended-Release Tablets (Drug Release Calibrator, Single Unit)
CHLORPHENIRAMINE MALEATE REFERENCE STANDARD
CHLORPHENIRAMINE-D4 MALEATE
c-meton
dexchlorpheniramine maleate
Haynon
ibioton
piriton
teldrin
Chlorpheniramine maleate solution

MDL Number

MFCD00069225

Customs Code

2933399090

FAQ

What is 3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8)?

3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) is a synthetic organic compound with the molecular formula C16H19ClN2. It is a white to pale yellow solid with moderate solubility in organic solvents. Known for its aromatic structure and amine functionality, this compound is often used in pharmaceutical and chemical research. It has a distinctive chloro-substituted phenyl group and a dimethylamino pyridine moiety, contributing to its reactivity and potential applications.

What are the main uses of 3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8)?

3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) is primarily used in pharmaceutical research as a precursor for drug development. It is also employed in organic synthesis due to its versatile functional groups. The compound's unique structure makes it valuable in the creation of compounds for medicinal and industrial applications. Its use is mainly confined to controlled laboratory settings due to its chemical reactivity and potential hazards.

Is 3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) safe?

3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) is generally considered safe when handled properly. However, it can be harmful if inhaled, ingested, or comes into contact with skin or eyes. Safety measures include using personal protective equipment (PPE) and working in a well-ventilated area. It is classified as a chemical with potential toxicity, so compliance with safety standards is essential in its use and storage.

How should 3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) be stored?

3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (CAS: 113-92-8) should be stored in a cool, dry, and well-ventilated area, away from direct light and incompatible substances. It is best kept in a sealed, airtight container to prevent moisture absorption. Storage temperature should be below 25°C, and humidity levels should be low to maintain stability. Always ensure proper labeling and storage in a designated chemical storage cabinet.