Imipramine HCl (Clomipramine HCl EP Impurity B HCl)

Basic Information

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CAS Number

113-52-0

Molecular Formula

C19H25ClN2

Molecular Weight

316.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

171.0 to 175.0 deg-C

Boiling Point

403.1°Cat760mmHg

Density

1.041

Water Solubility

Soluble in water

Solubility

H2O: 50 mg/mL

SMILES

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Cl.CN(C)CCCN1c2ccccc2CCc3ccccc13

InChI

InChI=1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

InChIKey

XZZXIYZZBJDEEP-UHFFFAOYSA-N

LogP

4.296800000000004

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

291

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Toxicity

LD50 in mice, rats (mg/kg): 400, 490 orally; 110, 90 i.p. (Tobe)

Synonyms & References

English

Imipramine hydrochloride
10,11-Dihydro-N,N-dimithyl-5,H-dibenz[b,f]azepine-5-propanamine
5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride
5H-dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-,monohydrochloride
antideprinhydrochloride
chimoreptin
chrytemin
cocapimipramine25
deprinol
Imipramine (hydrochloride)
Imipramine hydrochloride solution
10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride
5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
10,11-Dihydro-N,N-dimethyl-5H-dibenzo[b,f]azepine-5-propanamine Hydrochloride
5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine Hydrochloride
10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine hydrochloride
g22355
imidol
ia-pram
imavate
iprogen
dynazina
efuranol
fujisawa
janimine
imipramine
Melipramine
Imidobenzyle
Antideprin
Melipramin
Berkomine

MDL Number

MFCD00012669

FAQ

What is Imipramine HCl (CAS: 113-52-0)?

Imipramine HCl, with CAS number 113-52-0, is a tricyclic antidepressant used for the treatment of depression and certain types of obsessive-compulsive disorder (OCD). It is also used in the management of enuresis and premenstrual dysphoric disorder.

What are the main uses of Imipramine HCl (CAS: 113-52-0)?

Imipramine HCl is primarily used as a tricyclic antidepressant to treat depression, OCD, enuresis, and premenstrual dysphoric disorder. It also has potential use in the management of anxiety disorders and certain types of chronic pain.

Is Imipramine HCl (CAS: 113-52-0) safe?

Imipramine HCl can be safe when used as prescribed by a healthcare provider, but it carries potential risks such as side effects like dry mouth, constipation, blurred vision, and more serious ones like cardiac arrhythmias and interactions with other drugs. It is important to follow safety guidelines and avoid driving or operating machinery.

How should Imipramine HCl (CAS: 113-52-0) be stored?

Imipramine HCl should be stored in a tightly sealed container at room temperature, between 15-30°C (59-86°F), away from direct light and moisture. It should be kept out of reach of children and pets, and away from heat sources. Proper storage helps maintain its stability and efficacy.