N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide

Basic Information

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CAS Number

112913-94-7

Molecular Formula

C14H19FN2O2

Molecular Weight

266.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

462.8±51.0°C at 760 mmHg

Flash Point

213.847°C

Refractive Index

1.521

SMILES

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CC(=O)NCC1CN(CCO1)CC2=CC=C(C=C2)F

InChI

InChI=1S/C14H19FN2O2/c1-11(18)16-8-14-10-17(6-7-19-14)9-12-2-4-13(15)5-3-12/h2-5,14H,6-10H2,1H3,(H,16,18)

InChIKey

IYDYAXXGLUZOJN-UHFFFAOYSA-N

LogP

1.1625999999999999

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

293

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide
2-Acetylamidomethyl-4-(4-fluorobenzyl)morpholine
2-ACETYLAMINOMETHYL-4-(4-FLUOROBENZYL)-MORPHOLINE
N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]acetamide
2-acetylaminomethyl-4-(4-fluorobenzyl)morpholine
N-((4-(4-Fluorobenzyl)
N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}acetamide
N-[[4-(4-Fluorobenzyl)-2-morpholinyl]methyl]acetamide
N-({4-[(4-FLUOROPHENYL)METHYL]MORPHOLIN-2-YL}METHYL)ACETAMIDE
IYDYAXXGLUZOJN-UHFFFAOYSA-N
2230AA
2-Acetylaminomethyl-4-(4-fluorobenzyl)-morpholine
SCHEMBL7370883
112913-94-7
DB-125607
AKOS015918415
N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]acetamide;N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide
Fluorobenzyl)morpholin-2-yl)methyl)acetamide
MFCD16619692
DS-17859
J-507703
DTXSID40443497
CS-0153951
SY033824
A802699
AC2963
AMY8684

MDL Number

MFCD16619692

Customs Code

2934999090

FAQ

What are the physical and chemical properties of N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7)?

N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7) is a white crystalline solid with a molecular weight of approximately 353.38 g/mol. It has limited water solubility and is soluble in organic solvents such as DMSO. The compound is known for its stability in air and is not highly reactive under normal conditions.

How is N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7) typically synthesized?

N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7) can be synthesized by reacting 4-(4-fluorobenzyl)morpholine with acetic anhydride in the presence of a catalytic amount of a suitable acid or base. The reaction is typically conducted in an organic solvent such as dichloromethane. The yield is usually high, and the product can be isolated by filtration and recrystallization.

What industries use N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7)?

N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7) is primarily used in the pharmaceutical industry for its potential as a drug intermediate. It can also find applications in research and development for its specific chemical properties.

What precautions should be taken when handling N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7)?

When handling N-((4-(4-Fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS: 112913-94-7), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure the work is conducted in a well-ventilated area or a fume hood. In case of spills, immediately clean up with appropriate materials and ensure the area is well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and safety instructions.