Mosapride citrate

Basic Information

View in Editor

CAS Number

112885-42-4

Molecular Formula

C27H33ClFN3O10

Molecular Weight

614.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

117-124°C

Boiling Point

549.2°Cat760mmHg

Flash Point

286°C

SMILES

View in Editor

CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

InChI

InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChIKey

HUZTYZBFZKRPFG-UHFFFAOYSA-N

LogP

1.842300000000002

Topological Polar Surface Area

208.95 Å²

Hydrogen Bond Donor/Acceptor

7 / 13

Complexity

749

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in male, female mice, rats (mg/kg): >3000, >3000, >3000, 1905 orally; >1000, 914, >1000, >1000 i.p.; all species >1000 s.c.; in male, female dogs (mg/kg): both >400 orally (Yatera)

Synonyms & References

English

TAK-370 citrate; AS-4370 citrat;TAK370 citrate; AS4370 citrat;TAK 370 citrate; AS 4370 citrat
DTXSID7046207
MF497J489P
4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide 2-hydroxypropane-1,2,3-tricarboxylate
HY-B0189A
HMS2234K07
NC00216
Tox21_111874
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-((4-fluorophenyl)methyl)-2-morpholinyl)methyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
MFCD01666680
TAK-370 citrate
DTXCID5026207
AS-4370
HMS2051P15
HMS3651O09
SW197596-2
UNII-MF497J489P
MOSAPRIDE CITRATE [MI]
D70344
4-Amino-5-chloro-2-ethoxy-N-[[4-[(4 -fluorophenyl)methyl]-2-morpholinyl]methyl]benzami de citrate
MLS006011997
Gasmot
112885-42-4
CHEMBL1733174
BM164611
CAS-112885-42-4
Rimopride citrate
BCP08880
(+-)-4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide citrate
Mosapride citrate- Bio-X
Q27283985

MDL Number

MFCD01666680

FAQ

What is Mosapride citrate (CAS: 112885-42-4)?

Mosapride citrate is a selective serotonin 5-HT4 receptor agonist, used in the treatment of gastrointestinal disorders such as dyspepsia and gastroparesis. It is a prodrug that is converted to mosapride in the stomach, which then exerts its pharmacological effects.

What are the main uses of Mosapride citrate (CAS: 112885-42-4)?

Mosapride citrate is primarily used for the treatment of functional dyspepsia, diabetic gastroparesis, and other gastrointestinal motility disorders. It enhances gastric emptying and improves symptoms such as upper abdominal pain and early satiety.

Is Mosapride citrate (CAS: 112885-42-4) safe?

Mosapride citrate is generally considered safe when used as prescribed. However, it is important to follow the dosage instructions and monitor for potential side effects such as dizziness, nausea, and palpitations. Patients should avoid driving or operating machinery if experiencing dizziness.

How should Mosapride citrate (CAS: 112885-42-4) be stored?

Mosapride citrate should be stored at room temperature (15-30°C) in a tight, light-resistant container, and protected from moisture. Keep it away from children and pets, and store it out of direct sunlight and heat sources. Do not freeze.