N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine

Basic Information

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CAS Number

112883-41-7

Molecular Formula

C21H23NO4

Molecular Weight

353.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C21H23NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,2-3,12-13H2,1H3,(H,22,25)(H,23,24)/t19-/m1/s1

InChIKey

VCFCFPNRQDANPN-LJQANCHMSA-N

LogP

4.1685000000000025

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

472

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

VCFCFPNRQDANPN-LJQANCHMSA-N
D-Norleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EN300-624037
N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-norleucine
Z1982491153
Fmoc-D-Nle-OH
MFCD00155639
HY-W008273
DTXSID20373243
AS-19000
A802682
(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)hexanoic acid
J-300349
AM82589
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid
Fmoc-D-norleucine
112883-41-7
CS-W008273
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
Fmoc-D-Nle-OH, >=98.0%
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
SCHEMBL7420121
Fmoc-D-2-aminocaproic acid
AKOS015918292
Fmoc-D-Norleucine
FMOC-D-2-AMINOCAPROIC ACID
[(9-fluorenyl)methoxycarbonyl]-D-norleucine
FMoc-D-Nle
FMOC-D-AHX(2)-OH
FMOC-D-ACPO(2)-OH
RARECHEM EM WB 0165

MDL Number

MFCD00155639

FAQ

What are the physical and chemical properties of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7) is a colorless solid with a molecular weight of approximately 348.36 g/mol. It has a high melting point and good solubility in organic solvents such as methanol and acetonitrile. This compound is known for its stability and moderate reactivity in certain organic reactions.

How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7) typically synthesized?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7) is synthesized through the coupling of fluorenylmethyl chloroformate with D-norleucine in the presence of a base like triethylamine. The reaction yields a high purity product with good selectivity and high yield.

What industries use N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7) is primarily used in the pharmaceutical and chemical research industries. It serves as a precursor in the synthesis of various bioactive compounds and is also used in the development of certain polymers and materials.

What precautions should be taken when handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7)?

When handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-norleucine (CAS: 112883-41-7), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store in a cool, dry place away from direct sunlight. Use a fume hood for all handling procedures to avoid inhalation. In case of spill, immediately clean up and refer to the Safety Data Sheet (SDS) for further instructions.