N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine | CAS No. 112883-40-6

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine

Basic Information

CAS Number

112883-40-6

Molecular Formula

C20H21NO4S

Molecular Weight

371.46 g/mol

AD

Basic Physical Properties

Melting Point

120-124 °C

Density

1.2820

Refractive Index

30 ° (C=1, DMF)

CSCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m1/s1

InChIKey

BUBGAUHBELNDEW-GOSISDBHSA-N

LogP

3.7314000000000025

Topological Polar Surface Area

75.63 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

478

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (((9H-Fluoren-9-yl)methoxy)carbonyl)-D-methionine
  • D-Methionine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • 112883-40-6
  • Fmoc-D-Met-OH
  • HY-W009049
  • F0594
  • M03369
  • (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanyl-butyric acid
  • N-Fmoc-D-methionine
  • CS-W009765
  • A847881
  • (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(methylthio)butanoic acid
  • (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acid
  • 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanyl-butyric acid
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanoic acid
  • DS-14999
  • J-300197
  • BUBGAUHBELNDEW-GOSISDBHSA-N
  • 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanyl-butyric acid;Fmoc-D-Met-OH
  • AC-17108
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine
  • EN300-1556130
  • F10554
  • SCHEMBL800305
  • DTXSID90426316
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-methionine (Fmoc-D-Met-OH)
  • PD196650
  • 112833-40-6
  • AM81981
  • Fmoc-D-methionine
  • Fmoc-D-Met-OH, 98%

MDL Number

MFCD00062958

FAQ

What regulatory guidelines apply to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6) falls under various regulatory frameworks such as REACH in the European Union and EPA regulations in the United States. It is important to comply with GHS classification for hazardous substances, ensuring proper labeling and handling. Additionally, FDA guidelines for pharmaceutical and food contact materials apply if used in these sectors.

Are there alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6) in synthesis?

Several alternatives can be used in the synthesis of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6), including D-methionine derivatives with different protecting groups. Common substitutes include benzyl-D-methionine and fluorenylmethyloxycarbonyl (Fmoc) protected methionine. These alternatives offer similar reactivity and can be used depending on the specific synthetic route.

What is the market or research trend for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6)?

The market for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6) is closely tied to its applications in pharmaceuticals and organic synthesis. Emerging research trends focus on its use as a synthetic intermediate for peptides and drugs. Market demand is influenced by pharmaceutical advancements, with a growing emphasis on personalized medicine and targeted drug delivery systems.

How should waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6) be handled?

Waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine (CAS: 112883-40-6) should be handled in compliance with local and international waste management regulations. Proper collection of waste is followed by incineration or professional waste disposal services. Environmental protection measures include minimizing waste generation and ensuring safe storage and transport to prevent contamination of soil and water resources.

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