7-Fluoro-2-methylquinoline

Basic Information

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CAS Number

1128-74-1

Molecular Formula

C10H8FN

Molecular Weight

161.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

45.0 to 49.0 deg-C

Boiling Point

120°C/15mmHg

Flash Point

195 °F

SMILES

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CC1=NC2=C(C=C1)C=CC(=C2)F

InChI

InChI=1S/C10H8FN/c1-7-2-3-8-4-5-9(11)6-10(8)12-7/h2-6H,1H3

InChIKey

AYSKNDXTWPNRKG-UHFFFAOYSA-N

LogP

2.6823200000000007

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1128-74-1
7-Fluoroquinaldine
AB12293
7-Fluoro-2-methylquinoline
DTXSID80381263
Quinoline, 7-fluoro-2-methyl-
SY018300
J-002856
SCHEMBL1193454
InChI=1/C10H8FN/c1-7-2-3-8-4-5-9(11)6-10(8)12-7/h2-6H,1H3
F0519
AYSKNDXTWPNRKG-UHFFFAOYSA-
7-fluoro-2-methyl-quinoline
A802679
FT-0633382
PS-6328
D90677
AYSKNDXTWPNRKG-UHFFFAOYSA-N
AKOS015853507
7-Fluoro-2-methylquinoline, 97%
MFCD02683029
7-FLUOROQUINALDINE
2-METHYL-7-FLUOROQUINOLINE
PubChem5896
7-fluoro-2-methylpyridine
2-methyl-7-flruoroquinoline
Quinoline,7-fluoro-2-methyl-
7-fluoranyl-2-methyl-quinoline
PC0635
SBB087524
FCH1118821

MDL Number

MFCD02683029

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 7-Fluoro-2-methylquinoline (CAS: 1128-74-1)?

7-Fluoro-2-methylquinoline (CAS: 1128-74-1) falls under the scope of the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), requiring appropriate hazard communication including labels and safety data sheets. In the European Union, it is subject to REACH regulations, which require registration of substances based on their tonnage. Additionally, FDA and EPA regulations may apply due to its potential use in pharmaceutical and industrial applications, requiring compliance with specific handling and disposal guidelines.

Are there alternatives to 7-Fluoro-2-methylquinoline (CAS: 1128-74-1) in synthesis?

Alternatives to 7-Fluoro-2-methylquinoline (CAS: 1128-74-1) include other fluoroquinolines and quinolines with different substituents, which can be used in various synthesis pathways. Common alternative reagents include 2-methylquinoline and its analogues, which can be more readily available or have differing reactivity profiles, making them useful in specific synthetic contexts.

What is the market or research trend for 7-Fluoro-2-methylquinoline (CAS: 1128-74-1)?

The market for 7-Fluoro-2-methylquinoline (CAS: 1128-74-1) is driven by its applications in pharmaceuticals, particularly as intermediates in the synthesis of antimalarial and anticancer drugs. Research trends focus on optimizing synthesis methods and exploring new applications in drug discovery. Price trends are influenced by supply chain dynamics and demand from pharmaceutical industries, with ongoing efforts to reduce costs through more efficient synthesis routes.

How should waste containing 7-Fluoro-2-methylquinoline (CAS: 1128-74-1) be handled?

Waste containing 7-Fluoro-2-methylquinoline (CAS: 1128-74-1) should be collected in appropriate containers, ensuring the integrity of the waste and preventing spillage. For disposal, it is recommended to use professional waste disposal services that specialize in chemical waste. Incineration or other chemical-specific disposal methods should be employed to minimize environmental impact. Proper environmental protection measures, such as containment and neutralization, are essential to ensure compliance with regulations and environmental safety.