6-Fluoro-2-methylquinoline

Basic Information

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CAS Number

1128-61-6

Molecular Formula

C10H8FN

Molecular Weight

161.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

Solid

Melting Point

49-53 °C

Boiling Point

99°C/3mmHg

Solubility

Soluble in Chloroform.

Refractive Index

1.6

SMILES

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CC1=NC2=C(C=C1)C=C(C=C2)F

InChI

InChI=1S/C10H8FN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h2-6H,1H3

InChIKey

GPIARMSVZOEZCV-UHFFFAOYSA-N

LogP

2.6823200000000007

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

EINECS 214-439-2
FS-1041
MFCD00041233
MLS003269501
DTXSID50150180
6-Fluoro-2-methylquinoline
SY046958
5SLA2SME8U
EN300-97522
6-Fluoro-2-methylquinoline, 97%
1128-61-6
A802676
AR-683/43232140
HMS543B21
InChI=1/C10H8FN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h2-6H,1H3
6-Fluoroquinaldine
SMR000684607
Maybridge1_000571
AKOS000276642
CS-W008815
2-methyl-6-fluoroquinoline
6-Fluoro-2-methyl quinoline
GPIARMSVZOEZCV-UHFFFAOYSA-
6-fluoro quinaldine
F0300
6-Fluoroquinaldine;Quinoline, 6-fluoro-2-methyl-
SCHEMBL384813
BCP33162
Quinoline, 6-fluoro-2-methyl-
SB67644
1,1,2,3-TETRAMETHYL-1H-BENZ[E]INDOLIUMIODIDE

MDL Number

MFCD00041233

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 6-Fluoro-2-methylquinoline (CAS: 1128-61-6)?

6-Fluoro-2-methylquinoline (CAS: 1128-61-6) falls under the GHS (Global Harmonized System of Classification and Labelling of Chemicals) as a hazardous chemical requiring specific hazard communication and protective measures. It is also subject to REACH regulations in the European Union, which require registration and evaluation of substances. FDA and EPA regulations govern its use in products and environmental releases, ensuring safety and compliance with environmental protection standards.

Are there alternatives to 6-Fluoro-2-methylquinoline (CAS: 1128-61-6) in synthesis?

In the synthesis of 6-Fluoro-2-methylquinoline (CAS: 1128-61-6), alternative reagents such as 6-chloro-2-methylquinoline or 2-methylquinoline can be used, depending on the desired substituent. Isomers and analogs like 2-fluoro-6-methylquinoline are also available as potential alternatives. Careful selection should consider the reactivity and ease of synthesis for each compound.

What is the market or research trend for 6-Fluoro-2-methylquinoline (CAS: 1128-61-6)?

The market for 6-Fluoro-2-methylquinoline (CAS: 1128-61-6) is driven by its applications in pharmaceuticals and as a chemical intermediate. Research trends focus on its potential use in drug discovery and development, particularly in anti-inflammatory and anticancer therapies. Market demand is expected to grow with ongoing pharmaceutical research and advancements in synthetic methodologies.

How should waste containing 6-Fluoro-2-methylquinoline (CAS: 1128-61-6) be handled?

Waste containing 6-Fluoro-2-methylquinoline (CAS: 1128-61-6) should be collected in appropriate containers and handled according to the GHS guidelines. For disposal, incineration is a common method, but professional waste disposal services are recommended to ensure compliance with environmental regulations. Safe handling practices include proper labeling, minimizing exposure, and following all local, state, and national disposal guidelines.